Regioselective, Photocatalytic α-Functionalization of Amines.
| Autor: | Leng L; Department of Biochemistry, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-9038, United States., Fu Y; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Liu P; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States., Ready JM; Department of Biochemistry, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-9038, United States. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of the American Chemical Society [J Am Chem Soc] 2020 Jul 15; Vol. 142 (28), pp. 11972-11977. Date of Electronic Publication: 2020 Jun 30. |
| DOI: | 10.1021/jacs.0c03758 |
| Abstrakt: | Photocatalytic α-functionalization of amines provides a mild and atom-economical means to synthesize α-branched amines. Prior examples featured symmetrical or electronically biased substrates. Here we report a controllable α-functionalization of amines in which regioselectivity can be tuned with minor changes to the reaction conditions. |
| Databáze: | MEDLINE |
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