Managing the unexpected: Carcinosarcoma of the kidney parenchyma A case with the longest follow-up.
| Autor: | Ndrevataj D; Department of Urology, Policlinico San Martino Hospital, University of Genoa, Genoa, Italy., Mantica G; Department of Urology, Policlinico San Martino Hospital, University of Genoa, Genoa, Italy., Piol N; Department of Pathology, Policlinico San Martino Hospital, University of Genoa, Genoa, Italy., Cavo A; Oncology Unit, Villa Scassi Hospital, Genoa, Italy., Spina B; Department of Pathology, Policlinico San Martino Hospital, University of Genoa, Genoa, Italy., Toncini C; Department of Pathology, Policlinico San Martino Hospital, University of Genoa, Genoa, Italy., Boccardo F; Department of Oncology, Policlinico San Martino Hospital, University of Genoa, Genoa, Italy., Terrone C; Department of Urology, Policlinico San Martino Hospital, University of Genoa, Genoa, Italy. |
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| Jazyk: | angličtina |
| Zdroj: | Urologia [Urologia] 2021 Aug; Vol. 88 (3), pp. 251-254. Date of Electronic Publication: 2020 Jun 20. |
| DOI: | 10.1177/0391560320930439 |
| Abstrakt: | Introduction: We present the management of the second reported case of carcinosarcoma of the kidney parenchyma with malignant degeneration of both epithelial and mesenchymal components. Case Report: A 36-year-old woman came to our attention for an incidental sonographic finding of a lesion in the lower pole of the left kidney. A contrasted computed tomography scan confirmed the presence of a 50 × 52 mm 2 contrasted lesion in the left lower kidney pole. The patient underwent a challenging laparoscopic left partial nephrectomy and para-aortic lymphadenectomy. The histological examination led to the diagnosis of a carcinosarcoma of the kidney parenchyma with malignant degeneration of both epithelial and mesenchymal components. The patient underwent adjuvant chemotherapy with paclitaxel at 175 mg/m 2 plus carboplatin area under the curve 6 intravenously for six cycles. At a follow-up of 42 months, the patient is alive and does not show any local recurrences or distant metastases. Conclusion: A multi-disciplinary therapeutic approach, combined with an adequate doctor-patient relationship and a close and detailed follow-up, is of fundamental importance in obtaining good outcomes in such rare and challenging cases. |
| Databáze: | MEDLINE |
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