Diffuse midline glioma in the spinal cord with rapid respiratory deterioration.

Autor: Kamidani R; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Okada H; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Yasuda R; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Yoshida T; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Kusuzawa K; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Ichihashi M; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Kakino Y; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Oiwa H; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Kitagawa Y; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Fukuta T; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Suzuki K; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Okamoto H; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Miyake T; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Tachi M; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Kanda N; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Iwai C; Department of Orthopaedic Surgery Gifu University Graduate School of Medicine Gifu Japan., Shiba M; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Yamada N; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Nozawa S; Department of Orthopaedic Surgery Gifu University Graduate School of Medicine Gifu Japan., Nakayama N; Department of Neurosurgery Gifu University Graduate School of Medicine Gifu Japan., Doi T; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Fushimi K; Department of Orthopaedic Surgery Gifu University Graduate School of Medicine Gifu Japan., Yano H; Department of Neurosurgery Gifu University Graduate School of Medicine Gifu Japan., Tomita H; Department of Tumor Pathology Gifu University Graduate School of Medicine Gifu Japan., Yoshida S; Advanced Critical Care Center Gifu University Hospital Gifu Japan., Iwama T; Department of Neurosurgery Gifu University Graduate School of Medicine Gifu Japan., Ogura S; Advanced Critical Care Center Gifu University Hospital Gifu Japan.
Jazyk: angličtina
Zdroj: Acute medicine & surgery [Acute Med Surg] 2020 Mar 13; Vol. 7 (1), pp. e500. Date of Electronic Publication: 2020 Mar 13 (Print Publication: 2020).
DOI: 10.1002/ams2.500
Abstrakt: Background: Neurogenic acute respiratory failure is usually caused by either infection or vascular insufficiency. We report the case of a patient who developed acute respiratory failure secondary to a spinal tumor.
Case Presentation: A 32-year-old man, presenting with numbness and muscle weakness in his legs for 2 weeks, was transferred to our hospital with worsening quadriplegia and development of respiratory symptoms. We carried out emergent spinal decompression and initiated steroid pulse therapy, with no resolution of symptoms; a tumor incision biopsy after contrast cervical magnetic resonance imaging revealed an intraspinal tumor with a pathological diagnosis of World Health Organization grade IV glioma. The patient developed bradycardia, severe sepsis, status epilepticus, and cardiopulmonary arrest due to hypoxemia and was treated with chemoradiotherapy under mechanical ventilation. He was later transferred to another hospital for subacute care.
Conclusion: Acute respiratory failure caused by spinal tumors is uncommon. However, acute care practitioners should be mindful of neoplastic lesions as a potential cause.
Competing Interests: Approval of the research protocol: The need for ethics approval was waived as per the national guidelines. The study adhered to the Ethical Guidelines for Medical and Health Research Involving Human Subjects established by the government of Japan. Informed consent: Written informed consent was obtained from the patient for publication of this case report and any accompanying images. Registry and the registration no. of the study/trial: N/A. Animal studies: N/A. Conflict of interest: None.
(© 2020 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine.)
Databáze: MEDLINE
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