First molecular characterization of avian paramyxovirus-1 (Newcastle disease virus) in Botswana.

Autor: Kgotlele T; Botswana National Veterinary Laboratory, Private Bag 0035, Gaborone, Botswana., Modise B; Botswana National Veterinary Laboratory, Private Bag 0035, Gaborone, Botswana., Nyange JF; Botswana National Veterinary Laboratory, Private Bag 0035, Gaborone, Botswana., Thanda C; Botswana National Veterinary Laboratory, Private Bag 0035, Gaborone, Botswana., Cattoli G; Animal Production and Health Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Wagramer Strasse 5, P.O. Box 100, 1400, Vienna, Austria., Dundon WG; Animal Production and Health Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Wagramer Strasse 5, P.O. Box 100, 1400, Vienna, Austria. w.dundon@iaea.org.; Animal Production and Health Laboratory, IAEA, Freidenstrasse, 1, 2444, Seibersdorf, Austria. w.dundon@iaea.org.
Jazyk: angličtina
Zdroj: Virus genes [Virus Genes] 2020 Oct; Vol. 56 (5), pp. 646-650. Date of Electronic Publication: 2020 Jun 20.
DOI: 10.1007/s11262-020-01770-4
Abstrakt: Avian paramyxovirus-1 (APMV-1), the causative agent of Newcastle disease (ND) in domestic and wild avian species, has recently been reported and characterized in five southern African countries (i.e. Mozambique, Namibia, South Africa, Zambia and Zimbabwe). Since APMV-1s have never been characterized in Botswana, this study was undertaken to determine the genotype circulating in the country. Fourteen samples were collected from ND outbreaks in poultry in 2014, 2018 and 2019 and the complete fusion protein gene was sequenced. Phylogenetic analysis revealed that all of the viruses from Botswana clustered in genotype VII.2 (previously subgenotype VIIh) and that they were more related to viruses from South Africa and Mozambique than the other southern African countries (i.e. Namibia, Zambia and Zimbabwe).
Databáze: MEDLINE