Characteristics of genital herpes in Bilbao (Northern Spain): 12-year retrospective study.

Autor: Macho-Aizpurua M; Osakidetza, Hospital Universitario Basurto, Servicio de Microbiología Clínica y Control de Infección, Avenida Montevideo 18, 48013 Bilbao, Spain. Electronic address: mkl_iei@hotmail.com., Imaz-Pérez M; Osakidetza, Hospital Universitario Basurto, Servicio de Microbiología Clínica y Control de Infección, Avenida Montevideo 18, 48013 Bilbao, Spain., Álava-Menica JÁ; Osakidetza, Hospital Universitario Basurto, Servicio de Microbiología Clínica y Control de Infección, Avenida Montevideo 18, 48013 Bilbao, Spain., Hernández-Ragpa L; Osakidetza, Hospital Universitario Basurto, Servicio de Microbiología Clínica y Control de Infección, Avenida Montevideo 18, 48013 Bilbao, Spain., López-de-Munain-López MJ; Osakidetza, Hospital Universitario Basurto, Servicio de Enfermedades Infecciosas, Avenida Montevideo 18, 48013 Bilbao, Spain., Cámara-Pérez MM; Osakidetza, Hospital Universitario Basurto, Servicio de Enfermedades Infecciosas, Avenida Montevideo 18, 48013 Bilbao, Spain., Bilbao-González A; Osakidetza, Hospital Universitario Basurto, Unidad de Investigación, Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Avenida Montevideo 18, 48013 Bilbao, Spain., Díaz-de-Tuesta-Del Arco JL; Osakidetza, Hospital Universitario Basurto, Servicio de Microbiología Clínica y Control de Infección, Avenida Montevideo 18, 48013 Bilbao, Spain., Muñoz-Sánchez J; Osakidetza, Hospital Universitario Basurto, Servicio de Enfermedades Infecciosas, Avenida Montevideo 18, 48013 Bilbao, Spain., Basaras-Ibarzabal M; Universidad del País Vasco (UPV/EHU), Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Enfermería, Barrio Sarriena s/n, 48940 Leioa, Spain., Cisterna-Cancér R; Universidad del País Vasco (UPV/EHU), Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Enfermería, Barrio Sarriena s/n, 48940 Leioa, Spain.
Jazyk: English; Spanish; Castilian
Zdroj: Enfermedades infecciosas y microbiologia clinica (English ed.) [Enferm Infecc Microbiol Clin (Engl Ed)] 2021 May; Vol. 39 (5), pp. 234-240. Date of Electronic Publication: 2020 Jun 17.
DOI: 10.1016/j.eimc.2020.04.014
Abstrakt: Background: Herpes simplex virus type 2 (HSV-2) is the most common cause of genital herpes (GH), but genital infection by herpes simplex virus type 1 (HSV-1) is increasing. The aim of this study was to analyze and compare epidemiological characteristics of patients with GH.
Methods: Retrospective study conducted from January 2004 to December 2015 in patients with GH attended at two Sexually Transmitted Diseases (STDs) medical consultation of Bilbao-Basurto Integrated Health Organisation in Northern Spain. Patient's medical history was reviewed and data of interest was analyzed.
Results: One thousand three patients (524 male and 479 female) were reviewed. HSV-2 was detected in 74%. The proportion of HSV-1 increased during the study period, significantly in men (28% in 2004-2007 vs. 50% in 2012-2015). More female than male had HSV-1 infection (56% vs. 44%). The proportion of primary infection was higher among HSV-1 compared to HSV-2 (79% vs. 21%). Among the patients with HSV-1, primary infection was higher among men (86%) and in younger than 30 years. Recurrent GH was higher among HSV-2 infections (63%). In a multivariate model older age, geographic origin outside Spain, recurrent infection, prior contact with a partner's genital herpetic lesions, previous N. gonorrhoeae infection and prostitution were significantly associated with HSV-2 infection.
Conclusions: HSV-2 was the most common causative agent of GH, but the proportion of HSV-1 increased. Overall, antecedent of STD and sexual risk behaviors were more frequent in patients with genital HSV-2 infection.
(Copyright © 2020 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.)
Databáze: MEDLINE
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