Eczema herpeticum emerging during atopic dermatitis in infancy.

Autor: Ertuğrul A; Department of Pediatric Allergy and Clinical Immunology, Health Sciences University Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey., Emeksiz ZŞ; Department of Pediatric Allergy and Clinical Immunology, Health Sciences University Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey., Severcan EU; Department of Pediatric Allergy and Clinical Immunology, Health Sciences University Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey., Özmen S; Department of Pediatric Allergy and Clinical Immunology, Health Sciences University Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey., Bostancı İ; Department of Pediatric Allergy and Clinical Immunology, Health Sciences University Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey.
Jazyk: angličtina
Zdroj: The Turkish journal of pediatrics [Turk J Pediatr] 2020; Vol. 62 (3), pp. 514-519.
DOI: 10.24953/turkjped.2020.03.025
Abstrakt: Background: Eczema herpeticum (EH) is an acute disseminated viral infection that develops in the presence of an existing skin lesion, often on the ground of atopic dermatitis (AD). Morbidity and mortality of EH can be minimized by starting antiviral therapy at the earliest time in diagnosis.
Case: Herein we report five infants diagnosed with EH in the course of AD treatment. All patients had early onset, moderate to severe AD and needed intermittent topical corticosteroid (TCS) therapy. In physical examination, newly formed, TCS-resistant vesiculo-papular skin lesions were recognised on the present dermatitis. The presence of AD with food allergy and moderate to severe eosinophilia were other prominent findings.
Conclusion: All patients were misdiagnosed as AD exacerbation. Therefore, EH should be considered in the differential diagnosis of AD exacerbation especially in the infants with moderate to severe AD.
Databáze: MEDLINE