Global evaluation of echocardiography in patients with COVID-19.

Autor:	Dweck MR; Centre for Cardiovascular Science, University of Edinburgh, UK., Bularga A; Centre for Cardiovascular Science, University of Edinburgh, UK., Hahn RT; Columbia University Irving Medical Center, NY, USA., Bing R; Centre for Cardiovascular Science, University of Edinburgh, UK., Lee KK; Centre for Cardiovascular Science, University of Edinburgh, UK., Chapman AR; Centre for Cardiovascular Science, University of Edinburgh, UK., White A; Centre for Cardiovascular Science, University of Edinburgh, UK., Salvo GD; University Hospital Padua, Paediatric Cardiology, Padua, Italy., Sade LE; Department of Cardiology, University of Baskent, Ankara, Turkey., Pearce K; University Hospital South Manchester, Cardiology, Wythenshawe, Manchester, UK., Newby DE; Centre for Cardiovascular Science, University of Edinburgh, UK., Popescu BA; Department of Cardiology, University of Medicine and Pharmacy 'Carol Davila'-Euroecolab, Emergency Institute for Cardiovascular Diseases 'Prof. Dr. C. C. Iliescu', Bucharest, Romania., Donal E; University of Rennes, CHU Rennes, Inserm, LTSI-UMR 1099, Rennes, France., Cosyns B; Centrum voor Hart en Vaatziekten, Universitair Ziekenhuis Brussel, Vrij Universiteit van Brussel, Brussels, Belgium., Edvardsen T; Department of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway., Mills NL; Centre for Cardiovascular Science, University of Edinburgh, UK.; Usher Institute, University of Edinburgh, UK., Haugaa K; Department of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Faculty of Medicine, University of Oslo, Oslo, Norway.
Jazyk:	angličtina
Zdroj:	European heart journal. Cardiovascular Imaging [Eur Heart J Cardiovasc Imaging] 2020 Sep 01; Vol. 21 (9), pp. 949-958.
DOI:	10.1093/ehjci/jeaa178
Abstrakt:	Aims: To describe the cardiac abnormalities in patients with COVID-19 and identify the characteristics of patients who would benefit most from echocardiography. Methods and Results: In a prospective international survey, we captured echocardiography findings in patients with presumed or confirmed COVID-19 between 3 and 20 April 2020. Patient characteristics, indications, findings, and impact of echocardiography on management were recorded. Multivariable logistic regression identified predictors of echocardiographic abnormalities. A total of 1216 patients [62 (52-71) years, 70% male] from 69 countries across six continents were included. Overall, 667 (55%) patients had an abnormal echocardiogram. Left and right ventricular abnormalities were reported in 479 (39%) and 397 (33%) patients, respectively, with evidence of new myocardial infarction in 36 (3%), myocarditis in 35 (3%), and takotsubo cardiomyopathy in 19 (2%). Severe cardiac disease (severe ventricular dysfunction or tamponade) was observed in 182 (15%) patients. In those without pre-existing cardiac disease (n = 901), the echocardiogram was abnormal in 46%, and 13% had severe disease. Independent predictors of left and right ventricular abnormalities were distinct, including elevated natriuretic peptides [adjusted odds ratio (OR) 2.96, 95% confidence interval (CI) 1.75-5.05) and cardiac troponin (OR 1.69, 95% CI 1.13-2.53) for the former, and severity of COVID-19 symptoms (OR 3.19, 95% CI 1.73-6.10) for the latter. Echocardiography changed management in 33% of patients. Conclusion: In this global survey, cardiac abnormalities were observed in half of all COVID-19 patients undergoing echocardiography. Abnormalities were often unheralded or severe, and imaging changed management in one-third of patients. (© The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology.)
Databáze:	MEDLINE
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