Imaging of peroxynitrite in drug-induced acute kidney injury with a near-infrared fluorescence and photoacoustic dual-modal molecular probe.
| Autor: | Liu HW; Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn., Zhang H, Lou X, Teng L, Yuan J, Yuan L, Zhang XB, Tan W |
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| Jazyk: | angličtina |
| Zdroj: | Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Jul 25; Vol. 56 (58), pp. 8103-8106. Date of Electronic Publication: 2020 Jun 17. |
| DOI: | 10.1039/d0cc01621g |
| Abstrakt: | A FRET-based probe for mapping the fluctuation of ONOO - in cisplatin-induced acute kidney injury was constructed. It exhibits ratiometric near infrared fluorescence and a dramatic decrease of its peak absorbance at 719 nm upon addition of ONOO - that is converted into remarkable signal changes in fluorescence and photoacoustic images respectively. |
| Databáze: | MEDLINE |
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