Eslicarbazepine for focal epilepsy and acute intermittent porphyria.

Autor: Herrera-Fortin T; University of Montreal Hospital Center, Montreal, Quebec, Canada., Pana R; University of Montreal Hospital Center, Montreal, Quebec, Canada., Wesolowska E; University of Montreal Hospital Center, Montreal, Quebec, Canada., Bourré-Tessier J; University of Montreal Hospital Center, Montreal, Quebec, Canada., Nguyen DK; University of Montreal Hospital Center, Montreal, Quebec, Canada.
Jazyk: angličtina
Zdroj: Epileptic disorders : international epilepsy journal with videotape [Epileptic Disord] 2020 Jun 01; Vol. 22 (3), pp. 349-352.
DOI: 10.1684/epd.2020.1171
Abstrakt: Porphyrias are rare genetic disorders which cause a deficiency in the enzymes involved in the biosynthesis of heme. The treatment of epilepsy in patients with acute intermittent porphyria can be difficult since many anticonvulsants can increase heme synthesis and trigger porphyric attacks. We report a patient with focal epilepsy successfully treated with eslicarbazepine without exacerbation of porphyria.
Databáze: MEDLINE
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