Artificial selection reveals the role of transcriptional constraints in the maintenance of life history variation.

Autor: Pick JL; Department of Evolutionary Biology and Environmental Studies University of Zurich Zurich 8057 Switzerland.; School of Biological, Earth and Environmental Sciences University of New South Wales Sydney Australia.; Current Address: Institute of Evolutionary Biology University of Edinburgh Edinburgh United Kingdom., Hatakeyama M; Department of Evolutionary Biology and Environmental Studies University of Zurich Zurich 8057 Switzerland.; Functional Genomics Center Zurich Zurich 8057 Switzerland., Ihle KE; Department of Evolutionary Biology and Environmental Studies University of Zurich Zurich 8057 Switzerland., Gasparini J; Laboratoire Ecologie and Evolution UMR 7625 Université Pierre et Marie Curie CNRS ENS Paris France., Haussy C; Laboratoire Ecologie and Evolution UMR 7625 Université Pierre et Marie Curie CNRS ENS Paris France., Ishishita S; Graduate School of Bioagricultural Sciences Nagoya University Nagoya 464-8602 Japan., Matsuda Y; Graduate School of Bioagricultural Sciences Nagoya University Nagoya 464-8602 Japan., Yoshimura T; Graduate School of Bioagricultural Sciences Nagoya University Nagoya 464-8602 Japan., Kanaoka MM; Graduate School of Science Nagoya University Nagoya 464-8601 Japan., Shimizu-Inatsugi R; Department of Evolutionary Biology and Environmental Studies University of Zurich Zurich 8057 Switzerland., Shimizu KK; Department of Evolutionary Biology and Environmental Studies University of Zurich Zurich 8057 Switzerland.; Kihara Institute for Biological Research Yokohama City University Yokohama 244-0813 Japan., Tschirren B; Centre for Ecology and Conservation University of Exeter Penryn TR10 9FE United Kingdom.
Jazyk: angličtina
Zdroj: Evolution letters [Evol Lett] 2020 Apr 07; Vol. 4 (3), pp. 200-211. Date of Electronic Publication: 2020 Apr 07 (Print Publication: 2020).
DOI: 10.1002/evl3.166
Abstrakt: The trade-off between reproduction and self-maintenance is a cornerstone of life history theory, yet its proximate underpinnings are elusive. Here, we used an artificial selection approach to create replicated lines of Japanese quail ( Coturnix japonica ) that differ genetically in their reproductive investment. Whole transcriptome sequencing revealed that females from lines selected for high reproductive output show a consistent upregulation of genes associated with reproduction but a simultaneous downregulation of immune genes. Concordant phenotypic differences in immune function (i.e., specific antibody response against keyhole limpet hemocyanin) were observed between the selection lines, even in males who do not provide parental care. Our findings demonstrate the key role of obligate transcriptional constraints in the maintenance of life history variation. These constraints set fundamental limits to productivity and health in natural and domestic animal populations.
Competing Interests: The authors declare no conflict of interest.
(© 2020 The Authors. Evolution Letters published by Wiley Periodicals LLC on behalf of Society for the Study of Evolution (SSE) and European Society for Evolutionary Biology (ESEB).)
Databáze: MEDLINE
Externí odkaz: