New strategies for managing adult gliomas.

Autor: Kirby AJ; Department of Basic and Clinical Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK., Finnerty GT; Department of Basic and Clinical Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK. gerald.finnerty@kcl.ac.uk.; Department of Neurology, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK. gerald.finnerty@kcl.ac.uk.
Jazyk: angličtina
Zdroj: Journal of neurology [J Neurol] 2021 Oct; Vol. 268 (10), pp. 3666-3674. Date of Electronic Publication: 2020 Jun 15.
DOI: 10.1007/s00415-020-09884-3
Abstrakt: Gliomas are hard to treat. Their prognosis has improved little over the past few decades. Fundamental therapeutic challenges such as treatment resistance, malignant progression, and tumour recurrence persist. New strategies are needed to advance the management and treatment of gliomas. Here, we focus on where those new strategies could emerge. We consider how recent advances in our understanding of the biology of adult gliomas are informing new approaches to their treatment.
(© 2020. The Author(s).)
Databáze: MEDLINE
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