Autor: |
Alberca RW; Laboratory of Medical Investigation-56, - Departament of Dermatology, - Faculty of Medicine, University of São Paulo, São Paulo, Brazil., Oliveira LM; Institute of Biomedical Sciences, - Departament of Immunology, - University of São Paulo, São Paulo, Brazil., Branco ACCC; Institute of Biomedical Sciences, - Departament of Immunology, - University of São Paulo, São Paulo, Brazil., Pereira NZ; Laboratory of Medical Investigation-56, - Departament of Dermatology, - Faculty of Medicine, University of São Paulo, São Paulo, Brazil., Sato MN; Laboratory of Medical Investigation-56, - Departament of Dermatology, - Faculty of Medicine, University of São Paulo, São Paulo, Brazil. |
Abstrakt: |
The current coronavirus disease-2019 (COVID-19) pandemic presents a huge challenge for health-care systems worldwide. Many different risk factors are associated with disease severity, such as older age, diabetes, hypertension, and most recently obesity. The incidence of obesity has been on the rise for the past 25 years, reaching over 2 billion people throughout the world, and obesity itself could be considered a pandemic. In this review, we summarize aspects involved with obesity, such as changes in the immune response, nutritional factors, physiological factors, and the gut-lung axis, that impact the viral response and the COVID-19 prognosis. |