The role of spread through air spaces (STAS) in lung adenocarcinoma prognosis and therapeutic decision making.

Autor: Toki MI; Yale University School of Medicine, Department of Pathology, New Haven, United States; National and Kapodistrian University of Athens, Greece. Electronic address: maria.toki@yale.edu., Harrington K; The Institute of Cancer Research/The Royal Marsden, London, United Kingdom., Syrigos KN; National and Kapodistrian University of Athens, Greece.
Jazyk: angličtina
Zdroj: Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2020 Aug; Vol. 146, pp. 127-133. Date of Electronic Publication: 2020 May 12.
DOI: 10.1016/j.lungcan.2020.04.026
Abstrakt: Spread through air spaces (STAS) was included as a novel pattern of invasion in lung adenocarcinoma by the World Health Organization in 2015. Since then, multiple studies have investigated the association of STAS with clinicopathological and molecular features and its implication in the prognosis of early stage lung cancer patients undergoing different surgery types. The aim of this comprehensive review is to present current data on the role of STAS and its perspective in lung adenocarcinoma management.
Competing Interests: Declaration of Competing Interest All authors have no conflict of interest to report.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE