| Autor: |
Campos C; Department of Health Sciences, Universidad Autónoma Metropolitana-Iztapalapa, Mexico City, Mexico., Lázaro-Rodríguez TG; Department of Health Sciences, Universidad Autónoma Metropolitana-Iztapalapa, Mexico City, Mexico., Hernández-Pérez E; Department of Health Sciences, Universidad Autónoma Metropolitana-Iztapalapa, Mexico City, Mexico., Rincón-Heredia R; Microscopy Core Unit, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico., Fernández FJ; Department of Biotechnology, Universidad Autónoma Metropolitana-Iztapalapa, Mexico City, Mexico. fjfp@xanum.uam.mx. |
| Abstrakt: |
Pexophagy is a peroxisome degradation process. The last two steps of penicillin biosynthesis in Penicillium rubens are carried out in peroxisomes. These organelles proliferate in large numbers during this process, so that after the penicillin secretion, their removal is essential as a regulatory mechanism. In this work, two pexophagy modes are described for the high-penicillin producing strain P. rubens P2-32-T, by transmission electron microscopy (TEM) on 24- and 48-h cultures (when maximum penicillin production is achieved). The obtained images show peroxisome phagocytosis by vacuoles in three different ways: macropexophagy, micropexophagy, and a new proposed model: unipexophagy. |
Full text from SpringerLink