Fournier's Gangrene in Females: Presentation and Management at a Tertiary Center.

Autor: Beecroft NJ; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH., Jaeger CD; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH., Rose JR; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH., Becerra CMC; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH., Shah NC; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH., Palettas MS; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH., Lehman A; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH., Posid T; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH., Jenkins LC; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH., Baradaran N; Department of Urology, The Ohio State University Wexner Medical Center, Columbus, OH. Electronic address: Nima.Baradaran@osumc.edu.
Jazyk: angličtina
Zdroj: Urology [Urology] 2021 May; Vol. 151, pp. 113-117. Date of Electronic Publication: 2020 Jun 09.
DOI: 10.1016/j.urology.2020.05.056
Abstrakt: Objective: To report and compare presentation and management of Fournier's Gangrene (FG) in female vs male patients at a single tertiary care center.
Methods: Patient demographics, clinical characteristics, treatments and outcomes were summarized and compared between males and females who were treated for FG from 2011 to 2018 at a single institution.
Results: Of the 143 patients treated for FG at our institution, 33 (23%) were female. Female patients were predominantly white (82%), with a median (IQR) age of 55 (46, 59). Median female boby mass index (BMI) was 42.1 (32, 50.4). Female patients' wound cultures were polymicrobial mix of gram positive and gram negative organisms. Median number of debridements for females was 2 (1,3). The most common anatomic region of gangrene involvement in females was labia (76%) followed by perineum (55%) and gluteus/buttocks (42%). Mortality rate during initial admission was 6% for females. Female patients had a higher median BMI than males (42.1 vs 33.7 respectively; P = .003). FG severity index, length of hospital stay, number of debridements, and wound cultures were comparable to males. The surgical team managing initial debridements differed with females managed primarily by general surgery and males primarily by urology. Mortality rate was comparable to men (6% vs 7%, P >.05).
Conclusion: Female patients with FG have greater BMI but similar clinical presentation, microbiologic characteristics and mortality rate compared to men. Urologists have little involvement during initial management for females at our institution.
(Copyright © 2020 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE