The association of periodontal disease with the complications of diabetes mellitus. A systematic review.

Autor: Nguyen ATM; The University of Sydney School of Dentistry, Faculty of Medicine and Health, University of Sydney, Sydney, Australia; Charles Perkins Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia. Electronic address: thng4956@uni.sydney.edu.au., Akhter R; The University of Sydney School of Dentistry, Faculty of Medicine and Health, University of Sydney, Sydney, Australia., Garde S; The University of Sydney School of Dentistry, Faculty of Medicine and Health, University of Sydney, Sydney, Australia., Scott C; Oral Health Clinic, Royal Prince Alfred Hospital, Sydney, Australia., Twigg SM; Charles Perkins Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia; Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, Australia., Colagiuri S; Charles Perkins Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia; The Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, University of Sydney, Sydney, Australia., Ajwani S; Oral Health Services, Sydney Dental Hospital, Sydney Local Health District, Australia., Eberhard J; The University of Sydney School of Dentistry, Faculty of Medicine and Health, University of Sydney, Sydney, Australia; Charles Perkins Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Jazyk: angličtina
Zdroj: Diabetes research and clinical practice [Diabetes Res Clin Pract] 2020 Jul; Vol. 165, pp. 108244. Date of Electronic Publication: 2020 Jun 08.
DOI: 10.1016/j.diabres.2020.108244
Abstrakt: This review investigated the association of periodontal disease with diabetes mellitus (DM) and diabetic complications. PubMed/MEDLINE was searched including search terms "periodontal" OR "periodontitis" AND "diabetic complications" OR "diabetic retinopathy" OR "diabetic nephropathy" OR "diabetic neuropathy" OR "cardiovascular disease diabetes" OR "myocardial infarction diabetes" OR "cerebrovascular disease diabetes" OR "stroke diabetes" OR "peripheral vascular disease diabetes". Fourteen studies included in this review consistently reported an increased risk for diabetic complications including microvascular, macrovascular and death in the presence of periodontal disease. Higher risks for diabetic retinopathy (odds ratios: 2.8-8.7), neuropathy (3.2-6.6), nephropathy (1.9-8.5), cardiovascular complications (1.28-17.7) and mortality (2.3-8.5) were reported for people with diabetes with periodontitis compared to those with diabetes who have no periodontitis. This novel review summarizes current data providing further evidence of a link between poor oral health and DM and its complications. It has also drawn attention to major limitations of the available data linking periodontal disease and diabetic complications.
Competing Interests: Declarations of interest No potential conflicts of interest relevant to this article were reported.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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