Oral and maxillofacial outcomes in children with microcephaly associated with the congenital Zika syndrome.

Autor:	Ribeiro RA; Graduate Program in Orthodontics, College of Dentistry, Hermínio Ometto Foundation-FHO, Araras, SP, Brazil., Mattos A; Hospital Geral Roberto Santos, Bahia State Department of Health, Salvador, BA, Brazil., Meneghim MC; Department of Community Dentistry, Piracicaba Dental School, FOP-UNICAMP, SP, Brazil., Vedovello SAS; Graduate Program in Orthodontics, College of Dentistry, Hermínio Ometto Foundation-FHO, Araras, SP, Brazil., Borges TMD; Department of Health-Dentistry, State University of Feira de Santana, BA, Brazil., Santamaria M; Graduate Program in Orthodontics, College of Dentistry, Hermínio Ometto Foundation-FHO, Araras, SP, Brazil.; Graduate Program in Biomedical Sciences, Hermínio Ometto Foundation-FHO, Araras, SP, Brazil.
Jazyk:	angličtina
Zdroj:	European journal of orthodontics [Eur J Orthod] 2021 Jun 08; Vol. 43 (3), pp. 346-352.
DOI:	10.1093/ejo/cjaa036
Abstrakt:	Introduction: The objective of this study is to assess the oral and maxillofacial characteristics of microcephalic children associated with congenital Zika syndrome (CZS). Methods: A cross-sectional, observational study was carried out with 61 patients with microcephaly/CZS born between June 2015 and September 2017 (29 boys and 32 girls, average age of 22.8 months) and a control group with 58 non-CZS children born in the same period (25 boys and 33 girls, average age of 23.8 months). The functional clinical analysis considered the labial and lingual frena, tongue anterior projection, oral escape, palate form, and first tooth eruption. For the craniofacial analysis, facial anthropometric points and the cephalic perimeter at the time were measured. Demographic data were collected from medical records, and a clinical exam was performed in order to register the intrabuccal characteristics and craniofacial measures. The chi-square test and Student's t-test were used with a significance level of 0.05. Results: The narrow palate form, tongue anterior projection, oral escape, and late first tooth eruption were significantly more present in the group with microcephaly/CZS. As for the craniofacial analysis, face width (Bi-Zi), mandible width (Go-Go), height of face upper third (Tr-G), and monthly growth of cephalic perimeter were significantly smaller, whereas height of face lower third (Sn-Gn) was significantly bigger in the group with microcephaly/CZS (P < 0.05). Conclusion: Children with microcephaly resulting from a congenital Zika infection showed functional, oral, and maxillofacial changes and smaller facial development in comparison with non-CZS children in the same age group. (© The Author(s) 2020. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
Databáze:	MEDLINE
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