Vitamin D, Folate, and Cobalamin Serum Concentrations Are Related to Brain Volume and White Matter Integrity in Urban Adults.
Autor: | Beydoun MA; Laboratory of Epidemiology and Population Sciences, The National Institute on Aging (NIA) The Intramural Research Program (IRP), The National Institutes of Health (NIH), Baltimore, MD, United States., Shaked D; Laboratory of Epidemiology and Population Sciences, The National Institute on Aging (NIA) The Intramural Research Program (IRP), The National Institutes of Health (NIH), Baltimore, MD, United States.; Department of Psychology, University of Maryland, Baltimore County, MD, United States., Hossain S; Laboratory of Epidemiology and Population Sciences, The National Institute on Aging (NIA) The Intramural Research Program (IRP), The National Institutes of Health (NIH), Baltimore, MD, United States., Beydoun HA; Department of Research Programs, Fort Belvoir Community Hospital, Fort Belvoir, VA, United States., Katzel LI; Geriatric Research Education and Clinical Center, Baltimore VA Medical Center, Baltimore, MD, United States.; Division of Gerontology & Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States., Davatzikos C; Section for Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States., Gullapalli RP; Department of Diagnostic Radiology, University of Maryland School of Medicine, Baltimore, MD, United States., Seliger SL; Division of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States., Erus G; Section for Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States., Evans MK; Laboratory of Epidemiology and Population Sciences, The National Institute on Aging (NIA) The Intramural Research Program (IRP), The National Institutes of Health (NIH), Baltimore, MD, United States., Zonderman AB; Laboratory of Epidemiology and Population Sciences, The National Institute on Aging (NIA) The Intramural Research Program (IRP), The National Institutes of Health (NIH), Baltimore, MD, United States., Waldstein SR; Department of Psychology, University of Maryland, Baltimore County, MD, United States.; Geriatric Research Education and Clinical Center, Baltimore VA Medical Center, Baltimore, MD, United States.; Division of Gerontology & Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States. |
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Jazyk: | angličtina |
Zdroj: | Frontiers in aging neuroscience [Front Aging Neurosci] 2020 May 25; Vol. 12, pp. 140. Date of Electronic Publication: 2020 May 25 (Print Publication: 2020). |
DOI: | 10.3389/fnagi.2020.00140 |
Abstrakt: | Background and objectives: Lower vitamin status has been linked to cognitive deficits, pending mechanistic elucidation. Serum 25-hydroxyvitamin D [25(OH)D], folate and cobalamin were explored against brain volumes and white matter integrity (WMI). Methods: Three prospective waves from Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) study were used [Baltimore, City, MD, 2004-2015, N = 183-240 urban adults (Age (Copyright © 2020 Beydoun, Shaked, Hossain, Beydoun, Katzel, Davatzikos, Gullapalli, Seliger, Erus, Evans, Zonderman and Waldstein.) |
Databáze: | MEDLINE |
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