Thermal and thermal damage responses during switching bipolar radiofrequency ablation employing bipolar needles: A computational study on the effects of different electrode configuration, input voltage and ablation duration.

Autor: Cheong JKK; School of Engineering, Monash University Malaysia, Bandar Sunway, Malaysia., Ooi EH; School of Engineering, Monash University Malaysia, Bandar Sunway, Malaysia.; Advanced Engineering Platform, Monash University Malaysia, Bandar Sunway, Malaysia., Ooi ET; School of Engineering and Information Technology, Faculty of Science and Technology, Federation University, Ballarat, Victoria, Australia.
Jazyk: angličtina
Zdroj: International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2020 Sep; Vol. 36 (9), pp. e3374. Date of Electronic Publication: 2020 Jun 22.
DOI: 10.1002/cnm.3374
Abstrakt: Recent studies have demonstrated the effectiveness of switching bipolar radiofrequency ablation (bRFA) in treating liver cancer. Nevertheless, the clinical use of the treatment remains less common than conventional monopolar RFA - likely due to the lack of understanding of how the tissues respond thermally to the switching effect. The problem is exacerbated by the numerous possible switching combinations when bRFA is performed using bipolar needles, thus making theoretical deduction and experimental studies difficult. This article addresses this issue via computational modelling by examining if significant variation in the treatment outcome exists amongst six different electrode configurations defined by the X-, C-, U-, N-, Z- and O-models. Results indicated that the tissue thermal and thermal damage responses varied depending on the electrode configuration and the operating conditions (input voltage and ablation duration). For a spherical tumour, 30 mm in diameter, complete ablation could not be attained in all configurations with 70 V input voltage and 5 minutes ablation duration. Increasing the input voltage to 90 V enlarged the coagulation zone in the X-model only. With the other configurations, extending the ablation duration to 10 minutes was found to be the better at enlarging the coagulation zone.
(© 2020 John Wiley & Sons, Ltd.)
Databáze: MEDLINE
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