| Autor: |
Grimm C; Neural Control of Movement Lab, HEST, ETH Zürich, Zurich, Switzerland., Balsters JH; Department of Psychology, Royal Holloway University of London, Egham, Surrey, UK., Zerbi V; Neural Control of Movement Lab, HEST, ETH Zürich, Zurich, Switzerland. |
| Jazyk: |
angličtina |
| Zdroj: |
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry [Neuroscientist] 2021 Apr; Vol. 27 (2), pp. 159-183. Date of Electronic Publication: 2020 Jun 06. |
| DOI: |
10.1177/1073858420923552 |
| Abstrakt: |
Human behavior is strongly influenced by our motivation to establish social relationships and maintain them throughout life. Despite the importance of social behavior across species, it is still unclear how neural mechanisms drive social actions. Rodent models have been used for decades to unravel the neural pathways and substrates of social interactions. With the advent of novel approaches to selectively modulate brain circuits in animal models, unprecedented testing of brain regions and neuromodulators that encode social information can be achieved. However, it is unclear which classes of social behavior and related neural circuits can be generalized across species and which are unique to humans. There is a growing need to define a unified blueprint of social brain systems. Here, we review human and rodent literature on the brain's social actuators, specifically focusing on social motivation. We discuss the potential of implementing multimodal neuroimaging to guide us toward a consensus of brain areas and circuits for social behavior regulation. Understanding the circuital similarity and diversity is the critical step to improve the translation of research findings from rodents to humans. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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