Ultrasound-guided foam sclerotherapy for chronic venous disease with ulcer. A prospective multiple outcome cohort study.

Autor: de Abreu GCG; Pontifícia Universidade Católica de Campinas - PUC-Campinas, Campinas, SP, Brasil., de Camargo O Jr; Pontifícia Universidade Católica de Campinas - PUC-Campinas, Campinas, SP, Brasil., de Abreu MFM; Hospital e Maternidade Celso Pierro, Serviço de Cirurgia Vascular e Endovascular, Campinas, SP, Brasil., de Aquino JLB; Pontifícia Universidade Católica de Campinas - PUC-Campinas, Campinas, SP, Brasil.
Jazyk: angličtina
Zdroj: Jornal vascular brasileiro [J Vasc Bras] 2020 Mar 10; Vol. 19, pp. e20180108. Date of Electronic Publication: 2020 Mar 10.
DOI: 10.1590/1677-5449.180108
Abstrakt: Background: Chronic Venous Disease (CVD) is the main cause of chronic leg ulcers. Varicose veins are the most frequent cause of venous leg ulcers (VLU). 50.9% of Brazilian women have varicose veins and ulcer prevalence is as high as 4%. Ultrasound-guided foam sclerotherapy (UGFS) is a low-cost treatment option for varicose veins.
Objectives: To analyze UGFS outcomes in patients with VLU.
Methods: Prospective consecutive single center cohort study. Patients with great saphenous vein (GSV) reflux and VLU were treated and followed-up for 180 days. The following were studied: quality of life (QoL), disease severity, healing, and elimination of GSV reflux. The Aberdeen questionnaire, a venous clinical severity score, and Duplex scanning (DS) results were analyzed.
Results: 22 patients aged 35 to 70 years were treated. There was improvement in quality of life, disease severity reduced, and ulcer diameter reduced (p < 0.001; ANOVA). 77.27% of VLU healed completely (95%CI: 59.76-94.78%). The dimensions of 20/22 VLU reduced (90.91%; 95%CI: 78.9-100%). GSV reflux was eliminated in 63.64% (95%CI: 43.54-83.74%). Men had greater QoL benefit and women had more complications. There were no severe complications. The VLU that had healed completely at the end of the study were smaller at baseline than those that did not completely heal. The GSV that were completely occluded at the end of the study were smaller at baseline than those that were not completely occluded (p < 0.05; Mann-Whitney).
Conclusion: The results suggest that most patients benefited from UGFS.
Competing Interests: Conflicts of interest: No conflicts of interest declared concerning the publication of this article.
Databáze: MEDLINE
Externí odkaz: