Acute Hypersensitivity Pneumonitis Associated With a High Ki-67 Proliferative Index.
| Autor: | Nabrinsky E; Internal Medicine, Advocate Lutheran General Hospital, Park Ridge, USA., Kamar A; Internal Medicine, Advocate Lutheran General Hospital, Park Ridge, USA., Mohammed Saeed D; Pathology, University of Illinois, Chicago, USA., Pins M; Pathology, Advocate Lutheran General Hospital, Park Ridge, USA., Stone A; Pulmonary and Critical Care Medicine, Advocate Lutheran General Hospital, Park Ridge, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2020 Apr 30; Vol. 12 (4), pp. e7905. Date of Electronic Publication: 2020 Apr 30. |
| DOI: | 10.7759/cureus.7905 |
| Abstrakt: | Hypersensitivity pneumonitis (HSP) is an interstitial lung disease caused by exposure to a large range of environmental antigens. Inhaling aerosolized particles leads to a heightened immune response. HSP comes in acute, subacute, or chronic forms, all with their own potential clinical and radiographic findings. Mycobacterium avium complex (MAC) is the most common nontuberculous mycobacteria and is known to cause HSP with certain exposures. However, although certain histologic findings can be seen with HSP, a high ki-67 proliferation index is unusual and more commonly associated with malignancy. In this report, we discuss a case of MAC that had acute HSP associated with a high ki-67 proliferative index. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2020, Nabrinsky et al.) |
| Databáze: | MEDLINE |
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