Unmet needs in sexual health in bladder cancer patients: a systematic review of the evidence.

Autor: Bessa A; King's College London, School of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), TOUR, Guy's Hospital, 3rd Floor Bermondsey Wing, London, SE1 9RT, UK. Agustina.m.bessa@gmail.com., Martin R; The Royal Marsden, Department Urology, London, UK., Häggström C; King's College London, School of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), TOUR, Guy's Hospital, 3rd Floor Bermondsey Wing, London, SE1 9RT, UK.; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.; Department of Biobank Research, Umeå University, Umeå, Sweden., Enting D; King's College London, School of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), TOUR, Guy's Hospital, 3rd Floor Bermondsey Wing, London, SE1 9RT, UK.; Department of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Amery S; Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Khan MS; Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Cahill F; King's College London, School of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), TOUR, Guy's Hospital, 3rd Floor Bermondsey Wing, London, SE1 9RT, UK., Wylie H; King's College London, School of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), TOUR, Guy's Hospital, 3rd Floor Bermondsey Wing, London, SE1 9RT, UK., Broadhead S; Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Chatterton K; Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Malde S; Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Nair R; Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Thurairaja R; Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Kumar P; The Royal Marsden, Department Urology, London, UK., Haire A; King's College London, School of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), TOUR, Guy's Hospital, 3rd Floor Bermondsey Wing, London, SE1 9RT, UK., Green S; King's College London, School of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), TOUR, Guy's Hospital, 3rd Floor Bermondsey Wing, London, SE1 9RT, UK., Northover M; Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Briggs K; Department of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Van Hemelrijck M; King's College London, School of Cancer and Pharmaceutical Studies, Translational Oncology & Urology Research (TOUR), TOUR, Guy's Hospital, 3rd Floor Bermondsey Wing, London, SE1 9RT, UK.
Jazyk: angličtina
Zdroj: BMC urology [BMC Urol] 2020 Jun 03; Vol. 20 (1), pp. 64. Date of Electronic Publication: 2020 Jun 03.
DOI: 10.1186/s12894-020-00634-1
Abstrakt: Background: Bladder cancer (BC) treatment can have a detrimental effect on the sexual organs of patients and yet assessment of sexual health needs has been greatly overlooked for these patients compared to those who have undergone other cancer therapies.
Methods: This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines in July 2019. Studies were identified by conducting searches for Medline (using the PubMed interface), the Cochrane Central Register of Controlled Trials (CENTRAL) and Ovid Gateway (Embase and Ovid) using a list of defined search terms.
Results: 15 out of 37 studies included men only, 10 studies women only and 11 both sexes. Most participants were aged 50 to 65 years. Most studies (n = 34) focused on muscle invasive BC and only three on non-muscle invasive BC. Measurements of sexual dysfunction, including erection, ejaculation, firmness and desire, were the most commonly used measurements to report sexual health in men. In women, lubrification/dryness, desire, orgasm and dyspareunia were the most commonly reported. Twenty-one studies evaluated sexual dysfunction based on validated questionnaires, two with a non-validated questionnaire and through interviewing participants.
Conclusion: While recognition of the importance of the inclusion of psychometric measurements to assess sexual health is growing, there is a lack of consistent measures to assess sexual health in BC. With the focus on QoL arising in cancer survivorship, further studies are needed to develop, standardize and implement use of sexual health questionnaires with appropriate psychometrics and social measures to evaluate QoL in BC patients.
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Databáze: MEDLINE
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