Histology, Monocytes
| Autor: | Espinoza VE; American University of the Caribbean School of Medicine, Emmady PD; UNC school of Medicine, Atrium Health |
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| Jazyk: | angličtina |
| Zdroj: | 2022 Jan. |
| Abstrakt: | Monocytes are white blood cells that derive from the bone marrow. A monocyte is part of the innate immune response and functions to regulate cellular homeostasis, especially in the setting of infection and inflammation.[1] They account for approximately 5% of circulating nucleated cells in normal adult blood.[2] The half-life of circulating monocytes is approximately one to three days.[3] Monocytopenia, a decrease in circulating monocytes, is a common finding in myelodysplastic syndromes.[4] While monocytosis, an increase in circulating monocytes, is a common finding in the peripheral blood, especially in association with infection, trauma, medications, autoimmune disease, and some malignancies.[1] When monocytosis is persistent and unexplained, the diagnosis of chronic myelomonocytic leukemia merits investigation.[5] (Copyright © 2022, StatPearls Publishing LLC.) |
| Databáze: | MEDLINE |
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