The Lymphocyte-to-monocyte Ratio Is an Independent Prognostic Indicator in Pancreatic Head Cancer that Correlates With Obstructive Jaundice.

Autor:	Takeuchi M; Department of Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan masahiro99@med.uoeh-u.ac.jp.; Department of Surgery 1, School of Medicine, University of Occupational and Environmental Health, Fukuoka, Japan., Mitsuyoshi M; Department of Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan.; Department of Surgery 1, School of Medicine, University of Occupational and Environmental Health, Fukuoka, Japan., Yoshida K; Department of Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan., Onoda M; Department of Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan., Iwamura M; Department of Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan., Furutani A; Department of Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan., Kawano K; Department of Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan., Katoh T; Department of Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan.
Jazyk:	angličtina
Zdroj:	Anticancer research [Anticancer Res] 2020 Jun; Vol. 40 (6), pp. 3371-3377.
DOI:	10.21873/anticanres.14320
Abstrakt:	Background/aim: Several indicators of systemic inflammation have been reported to predict the outcomes of patients with malignant tumors but have not been fully investigated. The aim of this study was to evaluate whether the preoperative lymphocyte-to-monocyte ratio (LMR) can predict the outcomes of patients with pancreatic head cancer. Patients and Methods: We studied 32 patients who underwent curative surgery for pancreatic head cancer in our hospital between 2006 and 2016. Patients were classified into high and low groups according to their LMR. Results: The low LMR group had a significantly lower survival rate than the high LMR group (p=0.0313). A multivariate analysis showed that the pretreatment LMR (p=0.01) was an independent risk factor for cancer-related death. The LMR was correlated with obstructive jaundice (p=0.001). Conclusion: Preoperative LMR is a significant predictor of the outcome after pancreaticoduodenectomy in patients with pancreatic head cancer. (Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
Databáze:	MEDLINE
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