| Autor: |
Ryzhkov FV; N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russia., Ryzhkova YE; N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russia., Elinson MN; N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russia., Vorobyev SV; Department of Organic Chemistry and Petroleum Chemistry, Gubkin Russian State University of Oil and Gas, 65 Leninsky Prospect, Moscow 119991, Russia., Fakhrutdinov AN; N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russia., Vereshchagin AN; N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russia., Egorov MP; N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russia. |
| Abstrakt: |
The Pot, Atom, and Step Economy (PASE) approach is based on the Pot economy principle and unites it with the Atom and Step Economy strategies; it ensures high efficiency, simplicity and low waste formation. The PASE approach is widely used in multicomponent chemistry. This approach was adopted for the synthesis of previously unknown hydroxyquinolinone substituted chromeno[2,3- b ]pyridines via reaction of salicylaldehydes, malononitrile dimer and hydroxyquinolinone. It was shown that an ethanol-pyridine combination is more beneficial than other inorganic or organic catalysts. Quantum chemical studies showed that chromeno[2,3- b ]pyridines has potential for corrosion inhibition. Real time 1 H NMR monitoring was used for the investigation of reaction mechanism and 2-((2 H -chromen-3-yl)methylene)malononitrile was defined as a key intermediate in the reaction. |
