Two-Photon-Induced [2 + 2] Cycloaddition of Bis-thymines: A Biocompatible and Reversible Approach.

Autor:	Ricci M; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium., Rutten MGTA; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium., Toyouchi S; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium., Nanayakkara S; School of Chemistry, Monash University, Clayton, VIC 3800, Australia., Fortuni B; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium., Vitale R; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium.; Laboratoire de Spectrochimie Infrarouge et Raman, Université de Lille, Villeneuve d'Ascq Cedex C5, 59655 Lille, France., Rocha S; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium., Wilson DA; Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands., Hofkens J; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium.; Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany., Saito K; School of Chemistry, Monash University, Clayton, VIC 3800, Australia., Uji-I H; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium.; Research Institute for Electronic Science, Hokkaido University, N20W10, Kita-Waird, Sapporo 001-0020, Japan.
Jazyk:	angličtina
Zdroj:	ACS omega [ACS Omega] 2020 May 12; Vol. 5 (20), pp. 11547-11552. Date of Electronic Publication: 2020 May 12 (Print Publication: 2020).
DOI:	10.1021/acsomega.0c00770
Abstrakt:	Despite having great value across a wide variety of scientific fields, two-photon polymerizations currently suffer from two significant problems: the need for photoinitiators, which generate toxic side products, and the irreversibility of the process. Hence, the design of a versatile approach that circumvents these issues represents a major scientific challenge. Herein, we report a two-photon absorption strategy where reversible [2 + 2] cycloaddition of bis-thymines was achieved without the need for any photoinitiator. The cycloaddition and cycloreversion reactions could be induced by simply changing the irradiation wavelength, and repeated writing and erasing cycles were performed. The simplicity, reversibility, and biocompatibility of this strategy open up a whole new toolbox for applications across a wide variety of scientific fields. Competing Interests: The authors declare no competing financial interest. (Copyright © 2020 American Chemical Society.)
Databáze:	MEDLINE
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