Takayasu's Arteritis Presenting Atypically in a Female Nigerian.

Autor: Odunlami GJ; Rheumatology Unit, Department of Medicine, OAUTHC, Ile-Ife, Nigeria., Okunola OO; Nephrology Unit, Department of Medicine, OAUTHC, Ile-Ife, Nigeria., Olaosebikan H; Rheumatology Unit,LASUTH,Ikeja;Lagos,Nigeria., Aderibigbe AS; Radiology Department, OAUTHC, Ile-Ife, Nigeria., Ajibade AI; Rheumatology Unit, Department of Medicine, OAUTHC, Ile-Ife,Nigeria.
Jazyk: angličtina
Zdroj: West African journal of medicine [West Afr J Med] 2020 Jul-Aug; Vol. 37 (3), pp. 284-289.
Abstrakt: Takayasu's arteritis (TA) is an idiopathic form of large vessel granulomatous vasculitis that mainly affects the aorta and its major branches, most frequently in young women under 50 years. While traditionally, it is a disease found commonly in Asia continent, it has also been reported from different parts of the world, albeit with a few reports from Sub-Sahara Africa. The clinical presentations are variable and are commonly from systemic inflammation, vascular occlusive diseases and aneurysm. Asymptomatic cases of TA have been documented and are usually discovered incidentally on physical examination. Common vascular symptoms from different series include vascular claudication, reduced or absent pulse, carotid bruit, hypertension and headache. Facial mononeuropathy and retinal ischaemic changes are rare findings in TA. However, occlusive disease of ulnar artery has not been reported in TA despite our extensive literature search. Here, we present a 48-year-old woman, who was admitted via the medical emergency with community acquired pneumonia but was incidentally diagnosed with Takayasu arteritis with lower motor neuron facial nerve palsy, unilateral blindness, and ulnar artery occlusion. Multidisciplinary management was instituted and patient was discharged after resolution of community acquired pneumonia, vascular claudication, and chronic headache. TA often presents asymptomatically and sometimes with atypical features and thus we suggest high index of suspicion and detailed cardio-vascular examination in young individuals with unexplained chronic headache, facial nerve palsy and visual symptoms.
Databáze: MEDLINE