A transgender man, a cisgender woman, and assisted reproductive technologies: a Brazilian case report.

Autor: Resende SS; Dra Suely Resende - Centro de Reprodução Humana Assistida - Campo Grande, MS, Brazil., Kussumoto VH; Dra Suely Resende - Centro de Reprodução Humana Assistida - Campo Grande, MS, Brazil., Arima FHC; Dra Suely Resende - Centro de Reprodução Humana Assistida - Campo Grande, MS, Brazil., Krul PC; Dra Suely Resende - Centro de Reprodução Humana Assistida - Campo Grande, MS, Brazil., Rodovalho NCM; Dra Suely Resende - Centro de Reprodução Humana Assistida - Campo Grande, MS, Brazil., Sampaio MRJ; Dra Suely Resende - Centro de Reprodução Humana Assistida - Campo Grande, MS, Brazil., Alves MM; Dra Suely Resende - Centro de Reprodução Humana Assistida - Campo Grande, MS, Brazil.
Jazyk: angličtina
Zdroj: JBRA assisted reproduction [JBRA Assist Reprod] 2020 Oct 06; Vol. 24 (4), pp. 513-516. Date of Electronic Publication: 2020 Oct 06.
DOI: 10.5935/1518-0557.20200024
Abstrakt: Transgender men are individuals who identify as men but were assigned female at birth. Gender-affirming medications include testosterone hormone therapy, known for its diverse effects throughout the body, which include endometrial atrophy and the induction of amenorrhea by suppressing ovulation, without however affecting the ovarian follicle pool. This paper reports the first case in Brazil involving a transgender man and a cisgender woman attempting to form a family. A 34-year-old transgender man and a 28-year-old woman came to our assisted reproduction service. He had been on testosterone for two years. At their initial consultation, testosterone therapy was discontinued. Controlled ovarian stimulation for the transgender man was achieved using a combination of recombinant gonadotropins FSH and LH. Pituitary blockage was performed using a GnRH antagonist protocol. Twenty follicles were aspirated and 16 oocytes were retrieved, 12 of which mature. They were inseminated with donor semen. On the fifth day of development, one high quality blastocyst was transferred to the cisgender woman, resulting in an ongoing pregnancy. Five supernumerary embryos were cryopreserved. Controlled ovarian stimulation with high quality oocytes, high quality embryos, and clinical pregnancy are possible for transgender men, even with a history of testosterone use.
Databáze: MEDLINE