Quality of life in infants with atopic dermatitis and their families.

Autor: Djurović MR; Clinic of Dermatology and Venereology, Clinical Centre of Montenegro, Faculty of Medicine, University of Montenegro, Podgorica, Montenegro., Janković J; Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Ćirković A; Institute of Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Spirić VT; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.; Clinic for Allergology and Immunology, Clinical Centre of Serbia, Belgrade, Serbia., Maksimović N; Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Timotijević ZS; Department of Dermatology, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia., Vukićević D; Institute of Pathology, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia., Mirković Z; Department of Internal Medicine, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia., Vitković L; Institute of Histology, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia., Janković S; Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Jazyk: angličtina
Zdroj: Postepy dermatologii i alergologii [Postepy Dermatol Alergol] 2020 Feb; Vol. 37 (1), pp. 66-72. Date of Electronic Publication: 2020 Mar 09.
DOI: 10.5114/ada.2020.93385
Abstrakt: Introduction: Atopic dermatitis (AD) is the most common chronic inflammatory skin disease, with a significant effect on quality of life (QoL).
Aim: To evaluate the impact of AD on QoL of Montenegrin infants and their parents and to identify predictors affecting their QoL.
Material and Methods: The cross-sectional study was conducted between August 2017 and July 2018 and included 186 infants with AD aged 0-4 years and their parents. The severity of disease was measured by the Three-Item Severity (TIS) score, while QoL was assessed with the Infants' Dermatitis Quality of Life Index (IDQOL) and the Dermatitis Family Impact (DFI) questionnaire.
Results: The mean overall scores were 14.72 for IDQOL and 17.78 for DFI. The positive correlation was observed between AD severity and both the IDQOL and DFI scores ( r = 0.61, p < 0.001 and r = 0.67, p < 0.001, respectively). The highest-scoring IDQOL items were "itching and scratching", and "child's mood". Poorer infants' QoL was associated with more serious AD ( B = 2.56; 95% confidence interval (CI): 2.08-3.04), concomitant atopic disease ( B = 3.86; 95% CI: 1.78-5.94), family history of atopic disease ( B = 3.80; 95% CI: 1.84-5.77), older age of the child ( B = 1.14; 95% CI: 0.20-2.07) and older age of the parent ( B = 0.28; 95% CI: 0.04-0.53). Similarly, parents had poorer QoL if their infants had more severe AD ( B = 2.56; 95% CI: 2.14-2.87), another atopic disease ( B = 2.91; 95% CI: 0.99-4.84) or family history of atopic disease ( B = 4.33; 95% CI: 2.57-6.09).
Conclusions: Our results demonstrate that AD has a significant negative impact on infants' QoL as well as on QoL of their parents.
Competing Interests: The authors declare no conflict of interest.
(Copyright: © 2020 Termedia Sp. z o. o.)
Databáze: MEDLINE
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