Successful therapeutic approach in a patient with elephantiasic pretibial myxedema.
| Autor: | Ferreira M; University Hospital, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil. Electronic address: marinaferreirajf@yahoo.com.br., Zacaron LH; University Hospital, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil., Valle AFD; University Hospital, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil., Gamonal ACC; Graduate and Post-Graduate Program in Dermatology, Faculdade Suprema, Juiz de Fora, MG, Brazil. |
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| Jazyk: | angličtina |
| Zdroj: | Anais brasileiros de dermatologia [An Bras Dermatol] 2020 Jul - Aug; Vol. 95 (4), pp. 469-472. Date of Electronic Publication: 2019 Nov 25. |
| DOI: | 10.1016/j.abd.2019.02.007 |
| Abstrakt: | Localized pretibial myxedema is a dermopathy whose treatment is a challenge in dermatology, occurring in 0.5-4% of patients with Graves' disease. This autoimmune thyroid condition stimulates the production of hyaluronic acid and glycosaminoglycans that are deposited particularly in the pretibial region. Clinically, it presents as a localized, circumscribed, and non-depressible infiltrate in plaques. Several treatment modalities have been proposed, and their results vary, with worse response observed in severe cases. This report presents the case of a patient with elephantiasic pretibial myxedema who was subjected to intralesional corticosteroid applications, resulting in an excellent and encouraging therapeutic response that was maintained. (Copyright © 2019 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. All rights reserved.) |
| Databáze: | MEDLINE |
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