Numerical working memory alters alpha-beta oscillations and connectivity in the parietal cortices.

Autor: Koshy SM; Center for Magnetoencephalography, University of Nebraska Medical Center (UNMC), Omaha, Nebraska, USA., Wiesman AI; Center for Magnetoencephalography, University of Nebraska Medical Center (UNMC), Omaha, Nebraska, USA.; Department of Neurological Sciences, UNMC, Omaha, Nebraska, USA.; Cognitive Neuroscience of Development & Aging (CoNDA) Center, UNMC, Omaha, Nebraska, USA., Proskovec AL; Center for Magnetoencephalography, University of Nebraska Medical Center (UNMC), Omaha, Nebraska, USA.; Department of Psychology, University of Nebraska Omaha, Omaha, Nebraska, USA., Embury CM; Center for Magnetoencephalography, University of Nebraska Medical Center (UNMC), Omaha, Nebraska, USA.; Cognitive Neuroscience of Development & Aging (CoNDA) Center, UNMC, Omaha, Nebraska, USA.; Department of Psychology, University of Nebraska Omaha, Omaha, Nebraska, USA., Schantell MD; Center for Magnetoencephalography, University of Nebraska Medical Center (UNMC), Omaha, Nebraska, USA.; Department of Neurological Sciences, UNMC, Omaha, Nebraska, USA.; Cognitive Neuroscience of Development & Aging (CoNDA) Center, UNMC, Omaha, Nebraska, USA., Eastman JA; Center for Magnetoencephalography, University of Nebraska Medical Center (UNMC), Omaha, Nebraska, USA.; Department of Neurological Sciences, UNMC, Omaha, Nebraska, USA.; Cognitive Neuroscience of Development & Aging (CoNDA) Center, UNMC, Omaha, Nebraska, USA., Heinrichs-Graham E; Center for Magnetoencephalography, University of Nebraska Medical Center (UNMC), Omaha, Nebraska, USA.; Department of Neurological Sciences, UNMC, Omaha, Nebraska, USA.; Cognitive Neuroscience of Development & Aging (CoNDA) Center, UNMC, Omaha, Nebraska, USA., Wilson TW; Center for Magnetoencephalography, University of Nebraska Medical Center (UNMC), Omaha, Nebraska, USA.; Department of Neurological Sciences, UNMC, Omaha, Nebraska, USA.; Cognitive Neuroscience of Development & Aging (CoNDA) Center, UNMC, Omaha, Nebraska, USA.
Jazyk: angličtina
Zdroj: Human brain mapping [Hum Brain Mapp] 2020 Sep; Vol. 41 (13), pp. 3709-3719. Date of Electronic Publication: 2020 May 27.
DOI: 10.1002/hbm.25043
Abstrakt: Although the neural bases of numerical processing and memory have been extensively studied, much remains to be elucidated concerning the spectral and temporal dynamics surrounding these important cognitive processes. To further this understanding, we employed a novel numerical working memory paradigm in 28 young, healthy adults who underwent magnetoencephalography (MEG). The resulting data were examined in the time-frequency domain prior to image reconstruction using a beamformer. Whole-brain, spectrally-constrained coherence was also employed to determine network connectivity. In response to the numerical task, participants exhibited robust alpha/beta oscillations in the bilateral parietal cortices. Whole-brain statistical comparisons examining the effect of numerical manipulation during memory-item maintenance revealed a difference centered in the right superior parietal cortex, such that oscillatory responses during numerical manipulation were significantly stronger than when no manipulation was necessary. Additionally, there was significantly reduced cortico-cortical coherence between the right and left superior parietal regions during the manipulation compared to the maintenance trials, indicating that these regions were functioning more independently when the numerical information had to be actively processed. In sum, these results support previous studies that have implicated the importance of parietal regions in numerical processing, but also provide new knowledge on the spectral, temporal, and network dynamics that serve this critical cognitive function during active working memory maintenance.
(© 2020 The Authors. Human Brain Mapping published by Wiley Periodicals, Inc.)
Databáze: MEDLINE
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