Using Cutaneous Receptor Vibration to Uncover the Effect of Transcranial Magnetic Stimulation (TMS) on Motor Cortical Excitability.

Autor: Rogić Vidaković M; Department of Neuroscience, Laboratory for Human and Experimental Neurophysiology (LAHEN), University of Split School of Medicine, Split, Croatia., Kostović A; Department of Neuroscience, Laboratory for Human and Experimental Neurophysiology (LAHEN), University of Split School of Medicine, Split, Croatia., Jerković A; Department of Neuroscience, Laboratory for Human and Experimental Neurophysiology (LAHEN), University of Split School of Medicine, Split, Croatia., Šoda J; Signal Processing, Analysis and Advanced Diagnostics Research and Education Laboratory (SPAADREL), University of Split Faculty of Maritime Studies, Split, Croatia., Russo M; Department of Electronics, Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture, University of Split, Split, Croatia., Stella M; Department of Electronics, Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture, University of Split, Split, Croatia., Knežić A; Department of Electronics, Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture, University of Split, Split, Croatia., Vujović I; Signal Processing, Analysis and Advanced Diagnostics Research and Education Laboratory (SPAADREL), University of Split Faculty of Maritime Studies, Split, Croatia., Mihalj M; Department of Neurology, Laboratory of Electromyoneurography, University Hospital of Split, Split, Croatia., Baban J; Faculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, Croatia., Ljubenkov D; Department of Electrical Engineering and Computer Science (EECS), KTH Royal Institute of Technology, Stockholm, Sweden., Peko M; Department of Electronics, Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture, University of Split, Split, Croatia., Benzon B; Department of Neuroscience, Laboratory for Human and Experimental Neurophysiology (LAHEN), University of Split School of Medicine, Split, Croatia., Hagelien MV; Department of Neuroscience, Laboratory for Human and Experimental Neurophysiology (LAHEN), University of Split School of Medicine, Split, Croatia., Đogaš Z; Department of Neuroscience, Laboratory for Human and Experimental Neurophysiology (LAHEN), University of Split School of Medicine, Split, Croatia.
Jazyk: angličtina
Zdroj: Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2020 May 27; Vol. 26, pp. e923166. Date of Electronic Publication: 2020 May 27.
DOI: 10.12659/MSM.923166
Abstrakt: BACKGROUND Little is known about how vibrational stimuli applied to hand digits affect motor cortical excitability. The present transcranial magnetic stimulation (TMS) study investigated motor evoked potentials (MEPs) in the upper extremity muscle following high-frequency vibratory digit stimulation. MATERIAL AND METHODS High-frequency vibration was applied to the upper extremity digit II utilizing a miniature electromagnetic solenoid-type stimulator-tactor in 11 healthy study participants. The conditioning stimulation (C) preceded the test magnetic stimulation (T) by inter-stimulus intervals (ISIs) of 5-500 ms in 2 experimental sessions. The TMS was applied over the primary motor cortex for the hand abductor pollicis-brevis (APB) muscle. RESULTS Dunnett's multiple comparisons test indicated significant suppression of MEP amplitudes at ISIs of 200 ms (P=0.001), 300 ms (P=0.023), and 400 ms (P=0.029) compared to control. CONCLUSIONS MEP amplitude suppression was observed in the APB muscle at ISIs of 200-400 ms, applying afferent signaling that originates in skin receptors following the vibratory stimuli. The study provides novel insight on the time course and MEP modulation following cutaneous receptor vibration of the hand digit. The results of the study may have implications in neurology in the neurorehabilitation of patients with increased amplitude of MEPs.
Databáze: MEDLINE