| Autor: |
Brown KG; Kate Garland Brown is a clinical research NP at Rockefeller University in New York City, where Bernadette Capili is director of the Heilbrunn Family Center for Research Nursing. The authors acknowledge Mary Jeanne Kreek, MD, Eduardo Butelman, PhD, and Brian Reed, PhD, for their assistance in providing scientific information during manuscript preparation. Contact author: Kate Brown, kbrown@mail.rockefeller.edu. This article incorporates research supported in part by grant no. UL1TR001866 from the National Center for Advancing Translational Sciences' Clinical and Translational Science Awards Program. The authors and planners have disclosed no potential conflicts of interest, financial or otherwise., Capili B |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of nursing [Am J Nurs] 2020 Jun; Vol. 120 (6), pp. 38-46. |
| DOI: |
10.1097/01.NAJ.0000668736.80609.4e |
| Abstrakt: |
Opioid use disorder (OUD) is a chronic, relapsing disease. Genetic variability, dysregulated stress system response, and history of opioid experimentation or escalating exposure all contribute to the likelihood of developing OUD, which produces complex brain changes that make it difficult to stop opioid use. Understanding the neurobiology of OUD helps nurses anticipate the behaviors of patients with OUD and approach them with empathy. Here, the authors discuss the pathophysiology of OUD, available screening tools, medical treatments, and behavioral interventions that have demonstrated efficacy in reducing substance use. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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