Efficacy of fenugreek seed extract on men's psychological and physical health: a randomized placebo-controlled double-blind clinical trial.
| Autor: | Hausenblas HA; School of Applied Health Sciences, Professor, Brooks Rehabilitation College of Healthcare Sciences, Jacksonville University, 2800 University Boulevard North, Jacksonville, FL32211, USA., Conway KL; Center for Health and Human Performance, Jacksonville University, Jacksonville, USA., Coyle KRM; Center for Health and Human Performance, Jacksonville University, Jacksonville, USA., Barton E; Center for Health and Human Performance, Jacksonville University, Jacksonville, USA., Smith LD; Center for Health and Human Performance, Jacksonville University, Jacksonville, USA., Esposito M; Center for Health and Human Performance, Jacksonville University, Jacksonville, USA., Harvey C; Center for Health and Human Performance, Jacksonville University, Jacksonville, USA., Oakes D; Center for Health and Human Performance, Jacksonville University, Jacksonville, USA., Hooper DR; Center for Health and Human Performance, Jacksonville University, Jacksonville, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of complementary & integrative medicine [J Complement Integr Med] 2020 May 22; Vol. 18 (2), pp. 445-448. Date of Electronic Publication: 2020 May 22. |
| DOI: | 10.1515/jcim-2019-0101 |
| Abstrakt: | Objectives: Limited research has examined the effects of fenugreek ( Trigonella foenum-graecum L.) supplementation to improve healthy younger men's aging male symptoms. The study objective was to examine whether a fenugreek seed extract would improve healthy men's aging male symptoms, health-related quality of life (HRQoL), grip strength, and anxiety. Methods: Randomized double-blind placebo-controlled trial was employed, using a parallel design, with assessments at baseline, Day 30, and Day 60. Healthy male volunteers (n = 57, mean age = 26.1 years) were randomized to: fenugreek 400 mg/d (n = 19), fenugreek 500 mg/d (n = 19), or placebo group (n = 19). Results: The fenugreek groups reported significant improvements in aging male symptoms, anxiety levels, grip strength, and indicators of HRQoL compared to the placebo group, p ' s < 0.05. No adverse events were reported. Conclusion: Fenugreek supplementation is an effective nutritional intervention for improving aging male symptoms, anxiety levels, grip strength, and aspects of HRQoL in healthy recreationally active men. Future researchers are encouraged to examine the health and ergogenic effects of fenugreek supplementation in hypogonadal and older populations. Trial Registration: Clinicaltrials.gov identifier NCT03528538. (© 2020 Walter de Gruyter GmbH, Berlin/Boston.) |
| Databáze: | MEDLINE |
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