Autor: |
Boyle A, Plinston C, Laing F, Mackenzie G, Will RG, Manson JC, Diack AB |
Jazyk: |
angličtina |
Zdroj: |
Emerging infectious diseases [Emerg Infect Dis] 2020 Jun; Vol. 26 (6), pp. 1300-1303. |
DOI: |
10.3201/eid2606.191116 |
Abstrakt: |
We investigated a clinical case of variant Creutzfeldt-Jakob Disease in a person heterozygous for methionine/valine at codon 129 of the prion protein gene and identified the same strain properties in variant Creutzfeldt-Jakob disease in methionine homozygous persons and in bovine spongiform encephalopathy. These results indicate no adaptation of the agent in a different genetic background. |
Databáze: |
MEDLINE |
Externí odkaz: |
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