Host range and susceptibility to Toxoplasma gondii infection in captive neotropical and Old-world primates.

Autor: Paula NF; Departamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Dutra KS; Departamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Oliveira AR; Departamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Santos DOD; Departamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Rocha CEV; Departamento de Patologia Geral, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Vitor RWA; Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Tinoco HP; Fundação de Parques Municipais e Zoobotânica de Belo Horizonte, Hospital Veterinário, Belo Horizonte, Brazil., Costa MELTD; Fundação de Parques Municipais e Zoobotânica de Belo Horizonte, Hospital Veterinário, Belo Horizonte, Brazil., Paixão TAD; Departamento de Patologia Geral, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Santos RL; Departamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Jazyk: angličtina
Zdroj: Journal of medical primatology [J Med Primatol] 2020 Aug; Vol. 49 (4), pp. 202-210. Date of Electronic Publication: 2020 May 20.
DOI: 10.1111/jmp.12470
Abstrakt: Background: Toxoplasmosis is an important disease affecting captive non-human primates. The goal of this study was to assess the seroprevalence and pathological findings of toxoplasmosis in different species of captive primates.
Methods: Six captive neotropical primates died naturally due to Toxoplasma gondii infection and were necropsied. Tissue samples were evaluated by histopathology and immunohistochemistry. Serum samples from 57 captive neotropical and Old-world primates housed at the Belo Horizonte zoological garden were analyzed by indirect fluorescent antibody test (IFAT), enzyme-linked immunosorbent assay (ELISA), and indirect hemagglutination assay (IHA).
Results: Neotropical primates had lesions compatible with toxoplasmosis with immunolabeled intralesional T gondii. All Old-World primates (10/10), but only three neotropical primates (3/47), all belonging to the Sapajus apella species (3/6), were serologically positive.
Conclusions: Our results suggest a higher susceptibility of neotropical primates to toxoplasmosis. However, this study also supports the hypothesis that Sapajus apella may be naturally resistant.
(© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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