Probiotics reduce anxiety-related behavior in zebrafish.

Autor:	Valcarce DG; IEO, Spanish Institute of Oceanography, Planta de Cultivos El Bocal, Barrio Corbanera, Monte, 39012, Santander, Spain., Martínez-Vázquez JM; IEO, Spanish Institute of Oceanography, Planta de Cultivos El Bocal, Barrio Corbanera, Monte, 39012, Santander, Spain., Riesco MF; IEO, Spanish Institute of Oceanography, Planta de Cultivos El Bocal, Barrio Corbanera, Monte, 39012, Santander, Spain., Robles V; IEO, Spanish Institute of Oceanography, Planta de Cultivos El Bocal, Barrio Corbanera, Monte, 39012, Santander, Spain.; Cell Biology Area, Department of Molecular Biology, Universidad de León, 24071, León, Spain.
Jazyk:	angličtina
Zdroj:	Heliyon [Heliyon] 2020 May 14; Vol. 6 (5), pp. e03973. Date of Electronic Publication: 2020 May 14 (Print Publication: 2020).
DOI:	10.1016/j.heliyon.2020.e03973
Abstrakt:	There is increasing evidence that gut microbiome could have effects on neurological processes and on behavior. In this study we used the novel tank test (NTT) to analyze zebrafish exploring behavior after four months' supplementation with probiotics with probed antioxidant and anti-inflammatory properties. Results showed that prolonged ingestion of Lactobacillus rhamnosus CECT8361 and Bifidobacterium longum CECT7347 significantly alters the swimming pattern and mean swimming speed in the zebrafish model. After treatment, zebrafish strongly reduced their bottom-dwelling geotactic behavior when placed in a new tank, which could be correlated to a lower state of anxiety. (© 2020 Published by Elsevier Ltd.)
Databáze:	MEDLINE
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