Effect of exercise on epicardial adipose tissue in adults: a systematic review and meta-analyses.

Autor: Colonetti T; Laboratory of Biomedicine Translational, Postgraduate Program in Health Sciences,, Universidade do Extremo Sul Catarinense (UNESC),, Criciúma, Santa Catarina, Brazil., Grande AJ; Laboratory of Evidence-Based Health, Medical Course, Universidade Estadual de Mato Grosso do Sul (UEMS), Campo Grande, MS, Brazil., Amaral MC; Laboratory of Evidence-Based Health, Medical Course, Universidade Estadual de Mato Grosso do Sul (UEMS), Campo Grande, MS, Brazil., Colonetti L; Laboratory of Biomedicine Translational, Postgraduate Program in Health Sciences,, Universidade do Extremo Sul Catarinense (UNESC),, Criciúma, Santa Catarina, Brazil., Uggioni ML; Laboratory of Biomedicine Translational, Postgraduate Program in Health Sciences,, Universidade do Extremo Sul Catarinense (UNESC),, Criciúma, Santa Catarina, Brazil., da Rosa MI; Laboratory of Biomedicine Translational, Postgraduate Program in Health Sciences,, Universidade do Extremo Sul Catarinense (UNESC),, Criciúma, Santa Catarina, Brazil., Hernandez AV; Health Outcomes, Policy, and Evidence Synthesis (HOPES) Group, University of Connecticut School of Pharmacy, Storrs, Mansfield, CT, USA.; Vicerrectorado de Investigacion, Universidad San Ignacio de Loyola (USIL), Lima, Peru., Tse G; Xiamen Cardiovascular Hospital, Hong Kong, China., Liu T; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, the Second Hospital of Tianjin Medical University, Tianjin, China., Nerlekar N; Monash Cardiovascular Research Centre, Monash University and MonashHeart, Monash Health, Clayton, Australia., Biondi-Zoccai G; Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.; Mediterranea Cardiocentro, Naples, Italy., Neto MG; Physical Therapy Department, Federal University of Bahia-UFBA, Salvador, Bahia, Brazil.; Programa de Pós-Graduação em Medicina e Saúde, UFBA, Salvador, BA, Brazil., Durães AR; Programa de Pós-Graduação em Medicina e Saúde, UFBA, Salvador, BA, Brazil., Pontes-Neto O; Department of Neuroscience and Behavior, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil., Resende ES; Department of Neuroscience and Behavior, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil., Roever L; Department of Clinical Research, Federal University of Uberlândia, Rafael Rinaldi 431, Uberlândia, Minas Gerais, 38400384, Brazil. leonardoroever@hotmail.com.
Jazyk: angličtina
Zdroj: Heart failure reviews [Heart Fail Rev] 2021 Nov; Vol. 26 (6), pp. 1399-1411.
DOI: 10.1007/s10741-020-09965-5
Abstrakt: According to previous epidemiological studies, we can reduce the thickness of epicardial fat and improve cardiovascular risk factors through exercise, and the changes may depend on the form of exercise. We systemically reviewed published studies that evaluated exercise intervention on epicardial adipose tissue (EAT) levels. We included randomized controlled trials (RCTs) comparing one exercise with another exercise or diet for the treatment to reduce EAT. We used fixed effects models for meta-analyses; effects of exercise on outcomes were described as mean differences (MD) or standardized difference of means (SMD) was used, their 95% confidence intervals (CI). Five RCTs were included (n = 299), 156 in exercise group and 143 in the control. In comparison to the control group, exercise significantly reduced EAT (SMD - 0.57, 95%CI - 0.97 to - 0.18) and waist circumference (MD - 2.95 cm, 95%CI - 4.93 to - 0.97). Exercise did not have an effect on BMI (MD - 0.23 kg/m 2 , 95%CI - 0.73 to 0.27), weight (MD - 0.06 kg, 95%CI - 1.46 to 1.34), or HDL (SMD 0.26, 95%CI - 0.06 to 0.57).VO 2 was significantly increased by exercise (SMD 1.58, 95%CI 1.17 to 1.99). Risk of bias was high for 3 studies, and GRADE quality of evidence was very low to moderate. Exercise reduced epicardial adipose tissue and waist circumference, and did not have effect on weight, BMI, or HDL. Newer trials with better design and methods are necessary to improve the quality of the evidence. PROSPERO registration number (CRD42018096581).
(© 2020. Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz: