| Autor: |
Jacus JP; CH des vallées de l'Ariège, Consultations mémoire, Foix, France.; Univ. Lille, CNRS, CHU Lille, UMR 9193 - SCALab - Sciences Cognitives et Sciences Affectives, Lille, France., Mayelle A; Univ. Lille, CNRS, CHU Lille, UMR 9193 - SCALab - Sciences Cognitives et Sciences Affectives, Lille, France., Voltzenlogel V; CERPPS, Centre d'Etudes et de Recherche en Psychopathologie et Psychologie de la Santé, EA7411, Université Jean Jaurès, Toulouse, France., Cuervo-Lombard CV; CERPPS, Centre d'Etudes et de Recherche en Psychopathologie et Psychologie de la Santé, EA7411, Université Jean Jaurès, Toulouse, France., Antoine P; Univ. Lille, CNRS, CHU Lille, UMR 9193 - SCALab - Sciences Cognitives et Sciences Affectives, Lille, France. |
| Abstrakt: |
This study aimed to provide a model of awareness in Alzheimer's disease using the stage of the disease as a risk factor. Awareness was assessed using three methods (patient-caregiver discrepancy, prediction-performance discrepancy, clinical rating). Twenty-five healthy control subjects and sixty-one patients participated, with measures of cognition, apathy, depression, and awareness. These measures were introduced into a manual backward regression. Confounding factors impacting at least 15% of the exposure factor estimate were maintained in the model. Except for the prediction performance discrepancy, also presenting cognitive associations, the other awareness assessments suggested a major role of depression and apathy as impacting factors. |
