Effect of Midazolam on Vestibular Signs in Two Geriatric Dogs with Vestibular Disease.

Autor: Jang M; From Seoul National University College of Veterinary Medicine, Seoul, Republic of Korea (M.J., I.L.); and the Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri (F.A.M., A.B., J.R.D.)., Mann FA; From Seoul National University College of Veterinary Medicine, Seoul, Republic of Korea (M.J., I.L.); and the Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri (F.A.M., A.B., J.R.D.)., Bukoski A; From Seoul National University College of Veterinary Medicine, Seoul, Republic of Korea (M.J., I.L.); and the Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri (F.A.M., A.B., J.R.D.)., Dodam JR; From Seoul National University College of Veterinary Medicine, Seoul, Republic of Korea (M.J., I.L.); and the Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri (F.A.M., A.B., J.R.D.)., Lee I; From Seoul National University College of Veterinary Medicine, Seoul, Republic of Korea (M.J., I.L.); and the Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri (F.A.M., A.B., J.R.D.).
Jazyk: angličtina
Zdroj: Journal of the American Animal Hospital Association [J Am Anim Hosp Assoc] 2020 Jul/Aug; Vol. 56 (4), pp. e56402. Date of Electronic Publication: 2020 May 15.
DOI: 10.5326/JAAHA-MS-7014
Abstrakt: An abrupt balance impairment, including leaning, falling, and rolling, occurred after IV administration of 0.2 mg/kg midazolam as a preanesthetic medication in two geriatric dogs with a history of nystagmus and head tilt. In the second case, leaning, falling, and rolling recurred after recovery from general anesthesia but gradually ceased after IV administration of 0.01 mg/kg flumazenil. These two cases suggest that the IV administration of midazolam was responsible for the balance impairment in dogs who were suspected to have idiopathic peripheral vestibular disease.
Databáze: MEDLINE