Predictors of patient preference for either whole body magnetic resonance imaging (WB-MRI) or CT/ PET-CT for staging colorectal or lung cancer.

Autor: Miles A; Department of Psychological Sciences, Birkbeck, University of London, London, UK., Evans RE; Department of Psychological Sciences, Birkbeck, University of London, London, UK., Halligan S; Centre for Medical Imaging, University College London, Charles Bell House, UK., Beare S; Cancer Research UK, University College London Clinical Trials Centre, London, UK., Bridgewater J; UCL Cancer Institute, Paul O Gorman Building, London, UK., Goh V; Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, Strand, London, UK., Janes SM; Lungs for Living Research Centre, UCL Respiratory, Division of Medicine, University College London, London, UK., Navani N; Department of Thoracic Medicine, UCLH and Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK., Oliver A; Cancer patient representatives, c/o National Cancer Research Institute, London, UK., Morton A; Cancer patient representatives, c/o National Cancer Research Institute, London, UK., Morris S; Research Department of Applied Health Research, University College London, London, UK., Rockall A; Department of Surgery and Cancer, Imperial College London, Kensington, London, UK., Taylor SA; Centre for Medical Imaging, University College London, Charles Bell House, UK.
Jazyk: angličtina
Zdroj: Journal of medical imaging and radiation oncology [J Med Imaging Radiat Oncol] 2020 Aug; Vol. 64 (4), pp. 537-545. Date of Electronic Publication: 2020 May 14.
DOI: 10.1111/1754-9485.13038
Abstrakt: Introduction: Whole body magnetic resonance imaging (WB-MRI) may be more efficient in staging cancers, but can be harder for patients to tolerate. We examined predictors of patient preference for WB-MRI vs. CT/ PET-CT for staging colorectal or lung cancer.
Methods: Patients recruited prospectively to two multicentre trials comparing diagnostic accuracy of WB-MRI with standard staging scans were sent two questionnaires: the first, administered at trial registration, captured demographics, educational level and comorbidities; the second, administered after staging completion, measured emotional distress (GHQ-12), positive mood (PANAS), perceived scan burden, patients' beliefs about WB-MRI, and preference for either WB-MRI or CT (colorectal trial), WB-MRI or PET-CT (lung trial). Preference for WB-MRI or CT/ PET-CT was analysed using logistic regression.
Results: Baseline and post-staging questionnaires were completed by 97 and 107 patients, respectively. Overall, 56/107 (52%) preferred WB-MRI over standard scans and were more likely to have no additional comorbidities, higher positive mood, greater awareness of potential benefits of WB-MRI and lower levels of perceived WB-MRI scan burden. In adjusted analyses, only awareness of potential WB-MRI benefits remained a significant predictor (OR: 1.516, 95% CIs 1.006-2.284, P = 0.047). Knowledge that WB-MRI does not use radiation predicted preference (adjusted OR: 3.018, 95% CIs 1.099-8.288, P = 0.032), although only 45/107 (42%) patients were aware of this attribute.
Conclusions: A small majority of patients undergoing staging of colorectal or lung cancer prefer WB-MRI to CT/ PET-CT. Raising awareness of the potential benefits of WB-MRI, notably lack of ionizing radiation, could influence preference.
(© 2020 The Authors. Journal of Medical Imaging and Radiation Oncology published by John Wiley & Sons Australia, Ltd on behalf of Royal Australian and New Zealand College of Radiologists.)
Databáze: MEDLINE
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