The Effects of Initial Procalcitonin Levels on Mortality Rates in Geriatric Patients Undergoing Surgery.
| Autor: | Ongen İpek B; Medical Biochemistry, Maltepe University Faculty of Medicine, İstanbul, TUR., Karadeniz A; İnfectious Disease, Maltepe University, Istanbul, TUR., Sitar ME; Medical Biochemistry, Maltepe University Faculty of Medicine, Istanbul, TUR. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2020 Apr 10; Vol. 12 (4), pp. e7613. Date of Electronic Publication: 2020 Apr 10. |
| DOI: | 10.7759/cureus.7613 |
| Abstrakt: | Introduction The aim of the current study is to investigate the relationship between mortality rate in geriatric patients undergoing surgery with preoperative serum levels of procalcitonin, C-reactive protein, and erythrocyte sedimentation rate. Methods This was a single-center retrospective study, including three groups with 101 patients, who are older than 65 years of age. A retrospective investigation was carried out from the laboratory information system for all groups from January to December 2018. Group 1 included patients who had surgery and then mortality within 30 days after surgery. Group 2 included hospitalized patients who had surgery and no mortality within 30 days after surgery. Group 3 included outpatient patients, who had suspicion for a bacterial infection and then no surgery or no mortality within 30 days. Results When three group comparisons were made for procalcitonin, C-reactive protein, and erythrocyte sedimentation rate values, the p-value of one-way analysis of variance (ANOVA) was higher than 0.05 for procalcitonin and lower than 0.05 for C-reactive protein and erythrocyte sedimentation rate, suggesting that one or more groups were significantly different. When post-hoc multiple comparison methods were applied, there were statistically significant differences between Groups 1 and 3 for C-reactive protein and erythrocyte sedimentation rate. Conclusions Procalcitonin levels do not predict mortality following surgery. C-reactive protein and erythrocyte sedimentation rate are more useful biomarkers predicting mortality in geriatric patients undergoing surgery. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2020, Ongen İpek et al.) |
| Databáze: | MEDLINE |
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