Defense Peptides From the α-Hairpinin Family Are Components of Plant Innate Immunity.
| Autor: | Slavokhotova AA; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.; Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, Moscow, Russia., Rogozhin EA; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.; All-Russian Institute of Plant Protection, St. Petersburg-Pushkin, Russia.; Gause Institute of New Antibiotics, Moscow, Russia. |
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| Jazyk: | angličtina |
| Zdroj: | Frontiers in plant science [Front Plant Sci] 2020 Apr 23; Vol. 11, pp. 465. Date of Electronic Publication: 2020 Apr 23 (Print Publication: 2020). |
| DOI: | 10.3389/fpls.2020.00465 |
| Abstrakt: | Plant immunity represents a sophisticated system, including both basal and inducible mechanisms, to prevent pathogen infection. Antimicrobial peptides (AMPs) are among the innate immunity components playing a key role in effective and rapid response against various pathogens. This review is devoted to a small family of defense peptides called α-hairpinins. The general characters of the family, as well as the individual features of each member, including biological activities, structures of precursor proteins, and spatial structures, are described. Possible applications of α-hairpinin peptides in drug design are discussed. (Copyright © 2020 Slavokhotova and Rogozhin.) |
| Databáze: | MEDLINE |
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