Pharmaceuticals and Environment: a web-based decision support for considering environmental aspects of medicines in use.

Autor: Ramström H; Health and Medical Care Administration, Region Stockholm, Box 6909, SE-102 39, Stockholm, Sweden. helena.ramstrom@sll.se., Martini S; Formerly at Health and Medical Care Administration, Region Stockholm, Stockholm, Sweden., Borgendahl J; Sustainability Department, Regional Executive Office, Region Stockholm, Stockholm, Sweden., Ågerstrand M; Department of Environmental Science, Stockholm University, Stockholm, Sweden., Lärfars G; Health and Medical Care Administration, Region Stockholm, Box 6909, SE-102 39, Stockholm, Sweden., Ovesjö ML; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Quality, Development, MT and IT, Södersjukhuset, Stockholm, Sweden.
Jazyk: angličtina
Zdroj: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2020 Aug; Vol. 76 (8), pp. 1151-1160. Date of Electronic Publication: 2020 May 09.
DOI: 10.1007/s00228-020-02885-1
Abstrakt: Purpose: The database Pharmaceuticals and Environment is a non-commercial, freely available web-based decision support presenting compiled environmental information for pharmaceutical substances. It was developed by Region Stockholm and launched in 2016 at janusinfo.se. The purpose of this paper is to present the database, report on its current use, and reflect on lessons learned from developing and managing the database.
Methods: A standard operating procedure describes the work and content of the database, e.g., how information is retrieved, processed, and presented. Google Analytics was used for metrics. Issues related to the database have been discussed and handled by a reference group. The experiences from this work are presented.
Results: The database contains environmental hazard and risk information, primarily gathered from regulatory authorities and pharmaceutical companies. There are also assessments comparing substances within some groups of pharmaceuticals. The database is used by the Swedish Drug and Therapeutics Committees to include environmental aspects when recommending pharmaceuticals for health care providers. Page views show that users primarily look for information on commonly used substances, e.g., diclofenac and paracetamol/acetaminophen. Major problems for the development of the database are lack of data, lack of transparency, and discrepancies in the available environmental information.
Conclusion: In the absence of an adequate decision support produced by the regulatory authorities, we find the database Pharmaceuticals and Environment to be useful for Swedish Drug and Therapeutics Committees and health care providers, and it is our belief that the information can be valuable also in other settings.
Databáze: MEDLINE
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