A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon.

Autor:	Falconi-Agapito F; Department of Biomedical Sciences, Unit of Virology, Institute of Tropical Medicine, Nationalestraat 155, B-2000, Antwerp, Belgium; Unidad de Virología, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, 15102, Lima, Peru. Electronic address: francesca.falconi@upch.pe., Selhorst P; Department of Biomedical Sciences, Unit of Virology, Institute of Tropical Medicine, Nationalestraat 155, B-2000, Antwerp, Belgium. Electronic address: pselhorst@itg.be., Merino X; Unidad de Virología, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, 15102, Lima, Peru. Electronic address: xiomara.merino@upch.pe., Torres F; Hospital Santa Gema, Yurimaguas, Calle Progreso 405, Yurimaguas, Alto Amazonas, 16501, Loreto, Peru. Electronic address: fiori.tote@gmail.com., Michiels J; Department of Biomedical Sciences, Unit of Virology, Institute of Tropical Medicine, Nationalestraat 155, B-2000, Antwerp, Belgium. Electronic address: jmichiels@itg.be., Fernandez C; Hospital Santa Gema, Yurimaguas, Calle Progreso 405, Yurimaguas, Alto Amazonas, 16501, Loreto, Peru. Electronic address: connieaqp@yahoo.com., Talledo M; Unidad de Virología, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, 15102, Lima, Peru. Electronic address: michael.talledo.a@upch.pe., Ariën KK; Department of Biomedical Sciences, Unit of Virology, Institute of Tropical Medicine, Nationalestraat 155, B-2000, Antwerp, Belgium; Department of Biomedical Sciences, University of Antwerp, Universiteitsplein 1, 2610, Wilrijk, Belgium. Electronic address: karien@itg.be.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2020 Jul; Vol. 96, pp. 136-138. Date of Electronic Publication: 2020 May 06.
DOI:	10.1016/j.ijid.2020.04.087
Abstrakt:	We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E. (Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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