[Access to fertility preservation for adolescents and young adults aged 15 to 24 years with cancers in Auvergne, France].

Autor:	Grèze V; CHU de Clermont-Ferrand, hôpital Estaing, service d'hématologie-oncologie pédiatrique, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France; Université Clermont-Auvergne, Inserm-CIC 1405, unité CRECHE, Clermont-Ferrand, France., Mechdoud S; CHU de Clermont-Ferrand, hôpital Estaing, service d'hématologie-oncologie pédiatrique, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France., Vorilhon S; CHU de Clermont-Ferrand, hôpital Estaing, service de biologie et médecine de la reproduction, AMP-CECOS, Clermont-Ferrand, France., Isfan F; CHU de Clermont-Ferrand, hôpital Estaing, service d'hématologie-oncologie pédiatrique, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France., Rouel N; CHU de Clermont-Ferrand, hôpital Estaing, service d'hématologie-oncologie pédiatrique, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France; Université Clermont-Auvergne, Inserm-CIC 1405, unité CRECHE, Clermont-Ferrand, France., Chaput L; CHU de Clermont-Ferrand, hôpital Estaing, service de biologie et médecine de la reproduction, AMP-CECOS, Clermont-Ferrand, France., Brugnon F; CHU de Clermont-Ferrand, hôpital Estaing, service de biologie et médecine de la reproduction, AMP-CECOS, Clermont-Ferrand, France., Kanold J; CHU de Clermont-Ferrand, hôpital Estaing, service d'hématologie-oncologie pédiatrique, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France; Université Clermont-Auvergne, Inserm-CIC 1405, unité CRECHE, Clermont-Ferrand, France. Electronic address: jkanold@chu-clermontferrand.fr.
Jazyk:	francouzština
Zdroj:	Bulletin du cancer [Bull Cancer] 2020 Jul - Aug; Vol. 107 (7-8), pp. 773-778. Date of Electronic Publication: 2020 May 06.
DOI:	10.1016/j.bulcan.2020.03.013
Abstrakt:	Introduction: Cancers of adolescents and young adults have particular epidemiological specificities. The improvement in their survival should be accompanied by an increased consideration of the treatments' side effects, among which the potential decrease in fertility. The objective of the study was to describe the access to fertility preservation of these patients at the University Hospital of Clermont-Ferrand over a period of 3 years. Methods: During this retrospective descriptive study, various socio-demographic and clinical data were collected. Results: One hundred and fifty new cases of cancers were diagnosed in patients aged 15 to 24 years. Forty-four percent received at least one fertility consultation, 29 % for girls and 58 % for boys (P<0.001). The number of cases that did not result in fertility preservation was significantly higher for girls than boys (P=0.005). Fertility preservation was mainly achieved by cryopreservation of ovarian tissue in female adolescents, ovocytes in young women and sperm in boys. Discussion: We observed sex disparities in access to fertility preservation. Despite the existence of recommendations, progress remains to be made. The establishment of clinico-biological platforms should allow a better awareness of patients and professionals, and thus promote access to fertility preservation techniques for young patients with cancer. (Copyright © 2020 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.)
Databáze:	MEDLINE
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