A U-Shaped Relationship Between the Prevalence of Frailty and Body Mass Index in Community-Dwelling Japanese Older Adults: The Kyoto-Kameoka Study.

Autor: Watanabe D; National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo 162-8636, Japan.; Institute for Active Health, Kyoto University of Advanced Science, Kyoto 621-8555, Japan., Yoshida T; National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo 162-8636, Japan.; Institute for Active Health, Kyoto University of Advanced Science, Kyoto 621-8555, Japan.; Laboratory of Applied Health Sciences, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.; Senior Citizen's Welfare Section, Kameoka City Government, Kyoto 621-8501, Japan., Watanabe Y; National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo 162-8636, Japan.; Laboratory of Applied Health Sciences, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.; Faculty of Health and Sports Science, Doshisha University, Kyoto 610-0394, Japan., Yamada Y; National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo 162-8636, Japan.; Institute for Active Health, Kyoto University of Advanced Science, Kyoto 621-8555, Japan.; Laboratory of Applied Health Sciences, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan., Kimura M; Institute for Active Health, Kyoto University of Advanced Science, Kyoto 621-8555, Japan.; Laboratory of Applied Health Sciences, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan., Kyoto-Kameoka Study Group; National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo 162-8636, Japan.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2020 May 06; Vol. 9 (5). Date of Electronic Publication: 2020 May 06.
DOI: 10.3390/jcm9051367
Abstrakt: The relationship between body mass index (BMI) and frailty remains unclear. Using two validated frailty assessment tools, this study aimed to investigate the relationship between the prevalence of frailty and BMI in Japanese older adults. This cross-sectional study used baseline data of 7191 individuals aged ≥65 years, living in Kameoka City, Kyoto, Japan. The BMI was calculated based on self-reported height and body weight, and classified into six categories. Frailty was defined using two validated assessment tools, the Fried phenotype (FP) model and Kihon Checklist (KCL). We evaluated the relationship between frailty and BMI using a multivariate restricted cubic spline logistic regression. The prevalence of frailty defined using the FP model was 25.3%, 19.6%, 14.3%, 12.4%, 12.6%, and 19.4% for each BMI category of <18.5, 18.5-19.9, 20.0-22.4, 22.5-24.9, 25.0-27.4, and ≥27.5 kg/m 2 , respectively. The spline model showed a significant U-shaped relationship between BMI and the prevalence of frailty defined using both, KCL and FP models. This study found that the BMI range corresponding to lowest prevalence of frailty defined using both tools was 21.4-25.7 kg/m 2 . Thus, a healthy BMI may reduce the prevalence of frailty, and the risk of frailty needs to be evaluated in individuals who are underweight or overweight.
Competing Interests: Ajinomoto Co., Inc. provided funding to Y.Y. to conduct this study. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results. Moreover, this study is not related to any particular products of a company, and the results do not recommend any particular products.
Databáze: MEDLINE
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