Management of COVID-19: the risks associated with treatment are clear, but the benefits remain uncertain.

Autor: Zareifopoulos N; University Hospital of Patras Emergency Department. nizareifopoulos@gmail.com., Lagadinou M; Emergency Department, University Hospital of Patras. m_lagad2004@yahoo.gr., Karela A; Emergency Department, University Hospital of Patras. anastasia_karela@yahoo.gr., Platanaki C; Emergency Department, University Hospital of Patras. platanakic@yahoo.gr., Karantzogiannis G; Emergency Department, University Hospital of Patras. g.karatzogiannhs@gmail.com., Velissaris D; Emergency Department, University Hospital of Patras; Department of Internal Medicine, University of Patras School of Medicine, Patras. dimitrisvelissaris@yahoo.com.
Jazyk: angličtina
Zdroj: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace [Monaldi Arch Chest Dis] 2020 May 05; Vol. 90 (2). Date of Electronic Publication: 2020 May 05.
DOI: 10.4081/monaldi.2020.1342
Abstrakt: Even though the early reports from China provided advance warning of what was to come, the COVID-19 pandemic has spread throughout the world with devastating consequences. Emergency measures are being implemented to reduce the magnitude of the public health crisis, prevent healthcare facilities from becoming overwhelmed and reduce the death toll of the disease. Containment strategies to mitigate viral transmission and emergency measures to increase the capacity of each country to provide intensive care are at the forefront of the public health management of the epidemic, even though the detrimental social and psychological effects of quarantine are evident on a global scale. Optimal management of critically ill patients with COVID-19 is also unclear, and the initial suggestion for early intubation as in typical ARDS may have caused significant harm. The management of mild cases of confirmed infection is another point of controversy, as drugs which may be repurposed for COVID-19 treatment have significant, potentially irreversible toxic effects and their use in mild cases of a viral illness which is typically self-limited may be harmful.
Databáze: MEDLINE