| Autor: |
Ostroumova OD; I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.; Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Shikh EV; I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Rebrova EV; I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Ryazanova AY; Volgograd State Medical University, Volgograd, Russia., Moshetova LK; Russian Medical Academy of Continuous Professional Education, Moscow, Russia. |
| Jazyk: |
ruština |
| Zdroj: |
Vestnik oftalmologii [Vestn Oftalmol] 2020; Vol. 136 (2), pp. 107-116. |
| DOI: |
10.17116/oftalma2020136021107 |
| Abstrakt: |
Glaucoma is seen as a heterogeneous group of diseases characterized by optical neuropathy with associated visual field loss; one of the main risk factors for its development is increased intraocular pressure (IOP). In the case of drug-induced glaucoma (DIG), patients develop elevated IOP, optic neuropathy and visual field defects associated with the use of certain drugs. Corticosteroids are one of the most well-known classes of drugs that can cause an increase in IOP through the open-angle mechanism. Drug-induced glaucoma, which develops similarly to open-angle glaucoma, can also be caused by some non-steroidal anti-inflammatory agents, antibodies to the endothelial growth factor, etc. Classes of drugs that can cause angle-closure glaucoma include topical anticholinergic or sympathomimetic drops, tricyclic antidepressants, monoamine oxidase inhibitors, antihistamines, antiparkinsonian drugs, antipsychotic drugs, antispasmodics. Products containing sulfa group drugs can cause DIG due to a different closing angle mechanism involving a forward rotation of the ciliary body. It is important for medical practitioners to be aware of this unwanted drug reaction in order to prevent, detect and treat DIG. In the case of drug-induced increase in IOP, if the underlying disease allows discontinuation of drugs, this measure usually leads to normalization of IOP. In cases when the patient's IOP does not normalize after discontinuation of steroids or when they must continue to take corticosteroids, the administration of topical drugs for the treatment of glaucoma should be considered. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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